阈下创伤后应激障碍定义的实证研究。

IF 2.4 3区 医学 Q2 PSYCHIATRY
Alexandra B. Klein, Paula P. Schnurr, Michelle J. Bovin, Matthew J. Friedman, Terence M. Keane, Brian P. Marx
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引用次数: 0

摘要

长期以来,阈下创伤后应激障碍(PTSD)一直被认为是一个重要的结构,它可以识别出一个亚组的个体,这些个体报告了严重的PTSD症状和相关的残疾,但没有认可足够的症状来满足完整的PTSD诊断标准。不同的研究人员以不同的方式定义了亚阈值创伤后应激障碍,这使得很难在研究中解释这些发现。为了解决这个问题,我们系统地比较了符合九种不同亚阈值PTSD定义标准的个体与被诊断为完全PTSD或无PTSD(即未能满足亚阈值定义标准)的个体的患病率和相关临床结果。参与者是1082名退伍军人,他们在退伍军人出院后纵向登记处登记。使用DSM-5结构化临床访谈(SCID-5)确定PTSD和阈下PTSD诊断状态,并使用经验证的自我报告工具评估临床结果。在结果中,亚阈值定义通常确定了一组参与者,该组参与者与PTSD组和非PTSD组的参与者都是可区分的,rs=.02-.47。我们讨论了各种亚阈值定义的优点和缺点,并强调了在额外的结果和样本中评估这些定义的额外工作的必要性。在此期间,我们提出了阈值下PTSD的工作案例定义,即满足DSM-5四个症状标准中的任何三个(即标准B、C、D和e)以及标准a和标准F-H。研究结果表明,阈下PTSD是一个具有临床意义的结构。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An empirical investigation of definitions of subthreshold posttraumatic stress disorder

Subthreshold posttraumatic stress disorder (PTSD) has long been recognized as an important construct that identifies a subgroup of individuals who report significant PTSD symptoms and associated disability but do not endorse enough symptoms to meet the criteria for a full PTSD diagnosis. Different investigators have defined subthreshold PTSD in various ways, making it difficult to interpret findings across studies. To address this problem, we systematically compared individuals who met criteria for nine different subthreshold PTSD definitions with individuals diagnosed with either full PTSD or no PTSD (i.e., failed to meet the criteria for a subthreshold definition) with respect to prevalence and associated clinical outcomes of interest. Participants were 1,082 veterans enrolled in the Veterans After Discharge Longitudinal Registry. PTSD and subthreshold PTSD diagnostic status were determined using the Structured Clinical Interview for DSM-5 (SCID-5) and validated self-report instruments were used to assess clinical outcomes. Across outcomes, subthreshold definitions generally identified a group of participants that was distinguishable from participants in both the PTSD and no PTSD groups, rs = .02–.47. We discuss the benefits and drawbacks of various subthreshold definitions and highlight the need for additional work evaluating these definitions across additional outcomes and samples. In the interim, we propose a working case definition of subthreshold PTSD as meeting any three of the four DSM-5 symptom criteria (i.e., Criteria B, C, D, and E) along with Criterion A and Criteria F–H. The results suggest subthreshold PTSD is a clinically meaningful construct.

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来源期刊
CiteScore
5.80
自引率
6.10%
发文量
125
期刊介绍: Journal of Traumatic Stress (JTS) is published for the International Society for Traumatic Stress Studies. Journal of Traumatic Stress , the official publication for the International Society for Traumatic Stress Studies, is an interdisciplinary forum for the publication of peer-reviewed original papers on biopsychosocial aspects of trauma. Papers focus on theoretical formulations, research, treatment, prevention education/training, and legal and policy concerns. Journal of Traumatic Stress serves as a primary reference for professionals who study and treat people exposed to highly stressful and traumatic events (directly or through their occupational roles), such as war, disaster, accident, violence or abuse (criminal or familial), hostage-taking, or life-threatening illness. The journal publishes original articles, brief reports, review papers, commentaries, and, from time to time, special issues devoted to a single topic.
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