贝佐托单抗预防多次复发性艰难梭菌感染（CDI）患者复发的疗效。

IF 2.5 3区生物学 Q3 MICROBIOLOGY

Anaerobe Pub Date : 2023-11-04 DOI:10.1016/j.anaerobe.2023.102788

Andrew M. Skinner , Xing Tan , Colin Westman , Thomas Birris , Emily N. Drwiega , Michael S. Wang , Stuart Johnson

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引用次数: 0

摘要

在23名多重复发性艰难梭菌感染（mrCDI）患者中，在抗生素治疗结束时接受贝唑单抗治疗的患者中，持续的临床反应为91 % 在第30天和第78天 % 在90天时达到。抗生素治疗结束时给予贝佐托单抗对mrCDI患者有效。

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Efficacy of bezlotoxumab to prevent recurrent Clostridioides difficile infection (CDI) in patients with multiple prior recurrent CDI

Among 23 patients with multiply recurrent Clostridiodies difficile infection (mrCDI) who received bezlotoxumab at the end of antibiotic treatment a sustained clinical response of 91 % at 30 days and 78 % at 90 days was achieved. Bezlotoxumab administered at the end of antibiotic treatment was effective in patients with mrCDI.

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来源期刊

Anaerobe 生物-微生物学

CiteScore

5.20

自引率

8.70%

发文量

137

审稿时长

76 days

期刊介绍： Anaerobe is essential reading for those who wish to remain at the forefront of discoveries relating to life processes of strictly anaerobes. The journal is multi-disciplinary, and provides a unique forum for those investigating anaerobic organisms that cause infections in humans and animals, as well as anaerobes that play roles in microbiomes or environmental processes. Anaerobe publishes reviews, mini reviews, original research articles, notes and case reports. Relevant topics fall into the broad categories of anaerobes in human and animal diseases, anaerobes in the microbiome, anaerobes in the environment, diagnosis of anaerobes in clinical microbiology laboratories, molecular biology, genetics, pathogenesis, toxins and antibiotic susceptibility of anaerobic bacteria.