扩展异时共生作为研究复兴的一种方法。

IF 81.3 1区生物学 Q1 CELL BIOLOGY

Nature Reviews Molecular Cell Biology Pub Date : 2023-11-01 DOI:10.1038/s41580-023-00681-0

Bohan Zhang

引用次数: 0

摘要

在这篇 "贸易工具"（Tools of the Trade）文章中，张博涵（格拉迪舍夫实验室）讨论了如何利用延长小鼠异时同种异体培养（通过手术将循环系统连接一段较长的时间），然后再进行分离，从而揭示逆转哺乳动物衰老的潜在机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Extended heterochronic parabiosis as an approach to study rejuvenation

In this Tools of the Trade article, Bohan Zhang (Gladyshev lab) discusses how the use of extended heterochronic parabiosis in mice (surgical connection between circulatory systems for an extended period), followed by detachment, can shed light on potential mechanisms that reverse mammalian ageing.

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来源期刊

Nature Reviews Molecular Cell Biology 生物-细胞生物学

CiteScore

173.60

自引率

0.50%

发文量

118

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Molecular Cell Biology is a prestigious journal that aims to be the primary source of reviews and commentaries for the scientific communities it serves. The journal strives to publish articles that are authoritative, accessible, and enriched with easily understandable figures, tables, and other display items. The goal is to provide an unparalleled service to authors, referees, and readers, and the journal works diligently to maximize the usefulness and impact of each article. Nature Reviews Molecular Cell Biology publishes a variety of article types, including Reviews, Perspectives, Comments, and Research Highlights, all of which are relevant to molecular and cell biologists. The journal's broad scope ensures that the articles it publishes reach the widest possible audience.