来那度胺治疗复发性弥漫性大B细胞淋巴瘤腿型的长期完全反应：一例报告。

IF 2 4区医学 Q3 ONCOLOGY

Chemotherapy Pub Date : 2024-01-01 Epub Date: 2023-11-01 DOI:10.1159/000534784

Sabrina Zoli, Cinzia Pellegrini, Beatrice Casadei, Alessandro Broccoli, Lisa Argnani, Laura Nanni, Vittorio Stefoni, Pier Luigi Zinzani

引用次数: 0

摘要

引言：对于原发性皮肤弥漫性大B细胞淋巴瘤，腿型（PC DLBCL-LT），在复发的情况下，没有统一的二线治疗建议。病例介绍：我们介绍了一例老年复发/难治性PC DLBCL-LT患者，该患者使用来那度胺获得了延长的临床完全缓解。结论：来那度胺作为单一药物可产生意想不到的长期完全反应，毒性可控。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Prolonged Complete Response with Lenalidomide in a Relapsed Diffuse Large B-Cell Lymphoma, Leg-Type: A Case Report.

Introduction: For primary cutaneous diffuse large B-cell lymphoma, leg-type (PCDLBCL-LT), there are no uniform recommendations for second-line treatment in case of relapse.

Case presentation: Here, we present the case of an elderly relapsed/refractory PCDLBCL-LT patient who obtained a prolonged clinical complete remission with lenalidomide.

Conclusion: Lenalidomide as single agent led to an unexpected long complete response with manageable toxicity.

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来源期刊

Chemotherapy 医学-药学

CiteScore

5.80

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： This journal publishes original research articles and state-of-the-art reviews on all aspects of antimicrobial and antitumor chemotherapy. The results of experimental and clinical investigations into the microbiological and pharmacologic properties of antibacterial, antiviral and antitumor compounds are major topics of publication. Papers selected for the journal offer data concerning the efficacy, toxicology, and interactions of new drugs in single or combined applications. Studies designed to determine the pharmacokinetic and pharmacodynamics properties of similar preparations and comparing their efficacy are also included. Special emphasis is given to the development of drug-resistance, an increasing problem worldwide.