探讨肾功能评估：肌酸酐、半胱氨酸蛋白酶抑制剂C和估计肾小球滤过率，重点关注欧洲肾功能联盟方程。

IF 4 2区医学 Q1 MEDICAL LABORATORY TECHNOLOGY

Annals of Laboratory Medicine Pub Date : 2024-03-01 Epub Date: 2023-11-01 DOI:10.3343/alm.2023.0237

Hans Pottel, Pierre Delanaye, Etienne Cavalier

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引用次数: 0

摘要

血清肌酐和血清胱抑素C是用于计算估计肾小球滤过率（eGFR）的最广泛使用的肾脏生物标志物，用于估计肾损伤的严重程度。在这篇综述中，我们介绍了这些生物标志物的基本特征、它们的优缺点、一些基本历史以及目前最先进的实验室测量方法。它们的临床实用性以正常参考区间描述，以年龄相关参考区间图示，并在eGFR方程中使用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Exploring Renal Function Assessment: Creatinine, Cystatin C, and Estimated Glomerular Filtration Rate Focused on the European Kidney Function Consortium Equation.

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Exploring Renal Function Assessment: Creatinine, Cystatin C, and Estimated Glomerular Filtration Rate Focused on the European Kidney Function Consortium Equation.

Serum creatinine and serum cystatin C are the most widely used renal biomarkers for calculating the estimated glomerular filtration rate (eGFR), which is used to estimate the severity of kidney damage. In this review, we present the basic characteristics of these biomarkers, their advantages and disadvantages, some basic history, and current laboratory measurement practices with state-of-the-art methodology. Their clinical utility is described in terms of normal reference intervals, graphically presented with age-dependent reference intervals, and their use in eGFR equations.

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来源期刊

Annals of Laboratory Medicine MEDICAL LABORATORY TECHNOLOGY-

CiteScore

8.30

自引率

12.20%

发文量

100

审稿时长

6-12 weeks

期刊介绍： Annals of Laboratory Medicine is the official journal of Korean Society for Laboratory Medicine. The journal title has been recently changed from the Korean Journal of Laboratory Medicine (ISSN, 1598-6535) from the January issue of 2012. The JCR 2017 Impact factor of Ann Lab Med was 1.916.