喉保留手术治疗喉癌82例分析

Q4 Medicine
Katsuji Asano, Y. Somekawa, K. Takano, M. Kurose, Shigeru Koshiba, Yousuke Nagai, M. Myoujin, Hikaru Ikeda, M. Nishio
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引用次数: 0

摘要

作者共对82例喉癌患者施行保喉手术,其中原发病例59例,继发病例23例。82例患者的疾病特异性5年生存率为92.6%。82例喉部保留率为87.8%。对于早期喉癌的治疗(T1, 2),我们建议将保喉手术作为初始治疗的一种选择,因为在临床结果和日常生活中喉功能的保存方面,保喉手术并不亚于放疗。保喉手术作为复发的挽救性治疗,其喉保存率并不低于原发病例,似乎是一种有效的治疗复发患者的挽救性手术方法。11例手术缘组织病理检查阴性的5例局部复发。我们对这5例患者进行了全喉切除术。16例局部晚期肿瘤(T3, 4)中,5例(舌深肌侵1例,会厌前侵3例,环状软骨前壁侵1例)未出现局部复发,单纯手术即可成功局部控制。在适应证方面,局部进展期喉癌累及会厌前侵、舌深肌侵犯、环状软骨前壁侵犯的病例,由于局部控制,仅行手术,宜行保喉手术。然而,在复发的情况下,应考虑术后放疗,因为难以保留喉的功能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
82 cases of laryngeal preservation surgery for laryngeal cancer
The author performed larynx-conserving surgery on a total of 82 patients (59 primary cases and 23 secondary cases) of laryngeal cancer. The disease-specific 5-year survival rate of all 82 patients was 92.6%. The larynx con-servation rate was 87.8% in all 82 cases. In regard to the treatment of early-stage laryngeal cancer (T1, 2), we suggested that larynx-conserving surgery should be considered as an option for initial treatment because it is not inferior to radiotherapy in terms of clinical outcome and preservation of laryngeal function in daily life. Larynx-conserving surgery as a salvage treatment for recurrence did not present a lower laryngeal preservation rate than for primary cases, and seemed to be an effective method of salvage surgery for recurrent patients. these 11 cases, 5 cases whose surgical margins were diagnosed as negative on histopathological examination suffered local recurrence. We performed total laryngectomy as a salvage surgery on these 5 cases. Of the 16 cases of locally advanced cancer (T3, 4), 5 cases (1 case of deep tongue muscle invasion, 3 cases of anterior invasion of the epiglottis, and 1 case of anterior wall invasion of the cricoid cartilage) showed no local recurrence and local control was successfully achieved with surgery alone. Regarding indications, in the case of locally advanced laryngeal cancer involving anterior invasion of the epiglottis, deep tongue muscle invasion, and anterior wall invasion of the cricoid cartilage, larynx-conserving surgery appropriately indicated because the cases were local controlled with surgery alone. However, in the case of recurrence, postoperative radiotherapy should be considered because of the difficulty of preserving the function of the larynx.
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来源期刊
Japanese Journal of Head and Neck Cancer
Japanese Journal of Head and Neck Cancer Medicine-Otorhinolaryngology
CiteScore
0.10
自引率
0.00%
发文量
7
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