氯氮平和维护性电休克治疗1例35岁难治性精神分裂症和慢性势在必行的幻听患者

IF 0.7 Q4 PSYCHIATRY

Postepy Psychiatrii i Neurologii Pub Date : 2019-01-01 DOI:10.5114/ppn.2019.84356

P. Zakowicz, P. Wójciak, S. Dziuda, F. Rybakowski

{"title":"氯氮平和维护性电休克治疗1例35岁难治性精神分裂症和慢性势在必行的幻听患者","authors":"P. Zakowicz, P. Wójciak, S. Dziuda, F. Rybakowski","doi":"10.5114/ppn.2019.84356","DOIUrl":null,"url":null,"abstract":"Purpose: Despite progress in the treatment of schizophrenia, treatment resistance is reported in about 30% of patients. Various forms of treatment augmentation are used, but clozapine is generally considered to be the gold standard of care. In the management of patients with clozapine resistance adjunctive electroconvulsive therapy (ECT) courses have been proposed. In recent years particular attention has been paid to augmentation of clozapine with the maintenance electroconvulsive therapy (M-ECT). Case description: The paper presents a patient with treatment-resistant schizophrenia and chronic psychotic symptoms leading to self-destructive and suicidal behaviors. After concurrent treatment with clozapine and M-ECT her clinical status and functioning have improved. Comment: Maintenance-ECT used to augment clozapine in drug-resistant schizophrenia seems to be a safe and promising management option.","PeriodicalId":39142,"journal":{"name":"Postepy Psychiatrii i Neurologii","volume":null,"pages":null},"PeriodicalIF":0.7000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5114/ppn.2019.84356","citationCount":"0","resultStr":"{\"title\":\"Clozapine and maintenance electroconvulsive therapy in a 35-year-old patient with treatment-resistant schizophrenia and chronic imperative auditory hallucinations\",\"authors\":\"P. Zakowicz, P. Wójciak, S. Dziuda, F. Rybakowski\",\"doi\":\"10.5114/ppn.2019.84356\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Purpose: Despite progress in the treatment of schizophrenia, treatment resistance is reported in about 30% of patients. Various forms of treatment augmentation are used, but clozapine is generally considered to be the gold standard of care. In the management of patients with clozapine resistance adjunctive electroconvulsive therapy (ECT) courses have been proposed. In recent years particular attention has been paid to augmentation of clozapine with the maintenance electroconvulsive therapy (M-ECT). Case description: The paper presents a patient with treatment-resistant schizophrenia and chronic psychotic symptoms leading to self-destructive and suicidal behaviors. After concurrent treatment with clozapine and M-ECT her clinical status and functioning have improved. Comment: Maintenance-ECT used to augment clozapine in drug-resistant schizophrenia seems to be a safe and promising management option.\",\"PeriodicalId\":39142,\"journal\":{\"name\":\"Postepy Psychiatrii i Neurologii\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2019-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.5114/ppn.2019.84356\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Postepy Psychiatrii i Neurologii\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5114/ppn.2019.84356\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PSYCHIATRY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Postepy Psychiatrii i Neurologii","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5114/ppn.2019.84356","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PSYCHIATRY","Score":null,"Total":0}

引用次数: 0

摘要

目的:尽管精神分裂症的治疗取得了进展，但据报道，约30%的患者存在治疗耐药性。使用了各种形式的强化治疗，但氯氮平通常被认为是护理的金标准。在氯氮平耐药患者的治疗中，辅助电休克疗法(ECT)已被提出。近年来，人们特别关注氯氮平与维持电休克治疗(M-ECT)的增加。病例描述:本文介绍了一名患有治疗难治性精神分裂症和慢性精神病症状，导致自我毁灭和自杀行为的患者。经氯氮平和M-ECT联合治疗后，患者的临床状态和功能均有改善。评论:维持电痉挛疗法用于增加氯氮平治疗耐药精神分裂症似乎是一种安全且有前景的治疗选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Clozapine and maintenance electroconvulsive therapy in a 35-year-old patient with treatment-resistant schizophrenia and chronic imperative auditory hallucinations

Purpose: Despite progress in the treatment of schizophrenia, treatment resistance is reported in about 30% of patients. Various forms of treatment augmentation are used, but clozapine is generally considered to be the gold standard of care. In the management of patients with clozapine resistance adjunctive electroconvulsive therapy (ECT) courses have been proposed. In recent years particular attention has been paid to augmentation of clozapine with the maintenance electroconvulsive therapy (M-ECT). Case description: The paper presents a patient with treatment-resistant schizophrenia and chronic psychotic symptoms leading to self-destructive and suicidal behaviors. After concurrent treatment with clozapine and M-ECT her clinical status and functioning have improved. Comment: Maintenance-ECT used to augment clozapine in drug-resistant schizophrenia seems to be a safe and promising management option.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Postepy Psychiatrii i Neurologii Psychology-Clinical Psychology

CiteScore

0.90

自引率

0.00%

发文量

期刊介绍： The quarterly Advances in Psychiatry and Neurology is aimed at psychiatrists, neurologists as well as scientists working in related areas of basic and clinical research, psychology, social sciences and humanities. The journal publishes original papers, review articles, case reports, and - at the initiative of the Editorial Board – reflections or experiences on currently vivid theoretical and practical questions or controversies. Articles submitted to the journal are evaluated first by the Section Editors, specialists in the fields of psychiatry, clinical psychology, science of the brain and mind and neurology, and reviewed by acknowledged authorities in the respective field. Authors and reviewers remain anonymous to each other.