肥胖症及其治疗:综述

Leonardo Napples, Yung-Chieh Ching, Stephen Carol Rette, L. D’Mello
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引用次数: 2

摘要

体重增加是服用精神药物治疗后的反应。五十多年前,药物,例如阿米替林(依拉维尔)和锂,被认为与体重的显著增加无关,尽管精神药物的新时代,这种不受欢迎的症状一直存在。体重增加的数量是变化的,但当所有人都在一种精神状态下说,稳定剂和抗精神病药物比抗抑郁药更能引起体重增加。两种抗精神病药物氯氮平(Clozaril)和奥氮平(Zyprexa)与体重增加的最佳普遍性相关;高达31%的氯氮平患者和40%的奥氮平患者在治疗期间体重增加。一些性情稳定剂,例如丙戊酸钠(Depakote)同样也与高增重率有关。米氮平(雷米隆)和帕罗西汀(帕罗西汀)是抗抑郁药中最具增重潜力的两种抗抑郁药,尽管事实上除了安非他酮(安非他酮)外,增重在这一分类的大部分替代药物中占有重要地位。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Obesity and its Therapy: A Short Review
Weight increase is an understood reaction of treatment with psychotropic medications. Over fifty years prior, medications, for example, amitriptyline (Elavil) and lithium were known not connected with significant increments in weight and notwithstanding new eras of psychotropic medications, this unwelcome symptom has held on. The amount of weight is picked up changes however when all is said in one state of mind stabilizers and antipsychotics medications cause more generous weight pick up than antidepressants. Two antipsychotics, clozapine (Clozaril) and olanzapine (Zyprexa) are connected with the best pervasiveness of weight addition; up to 31% of patients treated with clozapine and 40% with olanzapine build their weight amid treatment. Some temperament stabilizers, for example, valproate (Depakote) likewise are connected with an also high rate of weight addition. Mirtazapine (Remeron) and paroxetine (Paxil) are two antidepressants with the best weight increase potential among the antidepressants in spite of the fact that aside from buproprion (Wellbutrin) weight addition has been accounted for among the greater part of alternate medications in this classification.
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