PHC患者热化疗栓塞后可溶性白细胞介素2受体和T淋巴细胞亚群的变化

Guo Wei-ping
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引用次数: 0

摘要

目的:观察PHC患者热化疗栓塞前后SIL-2R及T淋巴细胞亚群的变化,探讨其临床意义。方法:采用免疫荧光法和夹心ELISA法检测30例PHC患者热化疗栓塞前后的免疫状态,并与健康对照组进行比较。结果:PHC患者治疗后Th升高,Ts和SIL-2R降低(p0.01),而Ts和SIL-2R降低(p0.01)。结论:检测SIL-2R和T淋巴细胞亚群有助于了解免疫状态,对指导治疗效果和判断预后具有重要意义。医学文献显示,热化疗栓塞优于单纯化疗栓塞。[
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Changes of Soluble Interleukin 2 Receptor and T Lymphocytes Subsets in Patients with PHC after Thermochemoembolotherapy
Objective:To observe the changes of SIL-2R and T lymphocytes subsets in patients with PHC before and after thermochemoembolotherapy and evaluate their clinical significance.Methods:Immune fluorescent assay and sandwich ELISA were used to measure the immune state of 30 patients with PHC before and after thermochemoembolotherapy and compared them with that of health controls.Results:The level was lower while Ts and SIL-2R were higher in patients with PHC than that of health controls(p0.01) and Th elevated while Ts and SIL-2R declined (p0.01) after therapy.Conclusion:Measuring SIL-2R and T lymphocytes subsets is helpful to know the immune state and has significance in directing therapy effect and judging prognosis.For patients with PHC,thermochemoembolotherapy is superior to that of simplex chemoembolotherapy from medical document. [
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