脂质组学技术及其在医学研究中的应用

Journal of glycomics & lipidomics Pub Date : 2014-07-24 DOI:10.4172/2153-0637.1000115

Honglei Huang

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引用次数: 3

摘要

脂质是生物分子的不同家族，在生物学中具有重要的结构和信号作用。脂质分析测量及其鉴定和定量已成为一个重要的研究领域，特别是在生物医学科学中，因为许多人类病理与脂质代谢紊乱有关。本综述简要介绍了脂质分离和基于质谱的检测方法的实验工作流程，这些方法足以在临床环境中研究脂质谱。

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Lipidomics Techniques and its Applications in Medical Research

Lipids are diverse families of biomolecules that are involved in essential structural as well as signalling roles in biology. The analytical measurement of lipids and their identification & quantitation has become a major research area, in particular in biomedical science as many human pathologies are associated with lipid metabolism disorders. This review provides a brief overview over experimental workflows of lipid isolation and mass spectrometry based detection methods robust enough to study lipid profiles in a clinical context.

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Journal of glycomics & lipidomics

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