8例尼日利亚儿童牙源性纤维黏液瘤的治疗

Ku Omeje, I. Amole, O. Osunde, AA Efunkoya
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引用次数: 4

摘要

牙源性纤维黏液瘤(OFM)是一种良性,局部侵袭性和侵袭性的颌骨非转移性肿瘤。它们被认为是相对罕见的,并且已知来自牙齿起源的胚胎间充质成分。OFM的治疗取决于病变的大小及其性质和行为。不同的治疗方式,从刮除到根治性切除已被记录。本文回顾了尼日利亚一家三级卫生保健机构对8例组织学诊断为OFM的儿科患者的管理情况。这是一项回顾性研究,所有年龄在15岁及以下的患者在5年期间(2008年1月至2012年12月)就诊于卡诺Aminu Kano教学医院口腔颌面外科诊所,组织学诊断为OFM。获得的信息包括患者的人口统计学信息,以及他们的临床特征,如病变的解剖部位和侧面。整理的其他信息包括表现特征、症状开始、进行的治疗类型以及治疗结果。对数据进行分析,结果以频率和百分比表示。8例OFM患者中,男性居多(n = 5/8;62.5%)比女性受影响(n = 3/8;37.5%)。下颌骨(n = 5/8;62.5%)是最常见的发生部位,前下颌骨是最容易发生的部位(n = 4/8;50%)。7例患者切除病变并行周围骨切除术,而只有1例患者行骨切除术。这些患者已随访至少1年,随访期间未见复发。OFM会造成严重的面部畸形,并可能导致整个颌骨的破坏;这对一个成长中的孩子来说可能是严重的影响。及时的手术干预和随访已被证明是适当的治疗方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Management of Odontogenic Fibromyxoma in Pediatric Nigerian Patients: A Review of 8 Cases
Odontogenic fibromyxoma (OFM) is a benign, locally invasive and aggressive nonmetastasizing neoplasm of jaw bones. They are considered relatively rare and known to be derived from embryonic mesenchymal elements of dental origin. Treatment of OFM depends on the size of the lesion and on its nature and behavior. Varying treatment modalities ranging from curettage to radical excision have been documented.Aim; This paper is a review of management of 8 pediatric patients with histologically diagnosed OFM at a Nigerian tertiary health care facility. This was a retrospective study of all patients aged 15 years and below who presented to the Oral and Maxillofacial Surgery Clinic of Aminu Kano Teaching Hospital, Kano, over a 5-year period (January 2008 to December 2012), with a histologic diagnosis of OFM. The information obtained included patients' demographics, as well as their clinical characteristics such as the anatomical site and side of lesions. Other information collated included presenting features, the onset of symptoms, type of treatment carried out, as well as treatment outcome. The data were analyzed and the results presented as frequencies and percentages. Among the 8 patients with OFM, more males (n = 5/8; 62.5%) were affected than females (n = 3/8; 37.5%). The mandible (n = 5/8; 62.5%) was the most frequent site of occurrence, and the anterior mandible was the most favored location (n = 4/8; 50%). Seven patients had excision of the lesion with peripheral ostectomy of the underlying bone while only one patient had a bone resection. These patients have been followed up for at least 1 year, and no recurrence was observed throughout the follow-up period. OFM causes gross facial disfigurement and may result in the destruction of the entire jaw bone; the impact of which may be grave for a growing child. Prompt surgical intervention and follow-up have proven to be adequate management protocol.
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来源期刊
Annals of Medical and Health Sciences Research
Annals of Medical and Health Sciences Research HEALTH CARE SCIENCES & SERVICES-
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