糖尿病患者颈动脉病变:当代观点

N. Siddiqui, Asad Moosa, F. Shaikh, Waryam Saleh, Avgerinose Efthymios
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引用次数: 0

摘要

颈动脉疾病与缺血性脑卒中密切相关,是糖尿病患者发病率和死亡率的重要因素。颈动脉粥样硬化与脑血管或冠状动脉疾病之间的联系是明确的,指向高危患者。这种联系对于表现出高发病率的无症状心血管事件的糖尿病患者尤为重要,可以作为早期发现潜在动脉粥样硬化疾病的一种手段。颈动脉超声检查现在允许临床医生可视化颈动脉壁和管腔表面的特征,量化局部和全身动脉粥样硬化的严重程度,并更好地指导一级和二级预防策略的强度。颈动脉血运重建术仍然是高度狭窄患者的标准治疗方法,虽然围手术期事件和再狭窄发生率较高,但手术带来的益处仍然大于风险。目前的指南推荐颈动脉内膜切除术作为金标准手术;然而,颈动脉支架植入术可以作为一种有效的替代方法用于高风险的症状性糖尿病患者。最佳血糖控制和混杂危险因素管理可以改善短期和长期不良事件。引用本文:Siddiqui NA, Moosa A, Shaikh F, Saleh W, Efthymios A(2019)糖尿病患者颈动脉病变:当代视角。[J]血液淋巴杂志9:238。doi: 10.4172 / 2165 - 7831.1000238
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Carotid Artery Disease in Diabetic Patients: Contemporary Perspectives
Carotid artery disease is a significant contributor of diabetic patients’ morbidity and mortality driven by its strong association with ischemic stroke. The link between carotid atherosclerosis and cerebrovascular or coronary artery disease is otherwise well established pointing to a high risk patient. This link gets particularly important in diabetic patients who demonstrate high rates of silent cardiovascular events, as a means of early detection of underlying atherosclerotic disease. Carotid ultrasonography now allows clinicians to visualize the characteristics of the carotid wall and lumen surfaces, to quantify the severity of local and systemic atherosclerosis and better guide the intensity of primary and secondary prevention strategies. Carotid revascularization remains the standard of care for high grade stenosis and while higher perioperative events and restenosis rates may be anticipated the benefits derived from the procedure still outweigh the risks. Current guidelines recommend carotid endarterectomy as a gold standard procedure; however carotid artery stenting can be a valid alternative in high medical risk symptomatic diabetic patients. Optimal glycemic control and confounding risk factor management can ameliorate short and longer term adverse events. Citation: Siddiqui NA, Moosa A, Shaikh F, Saleh W, Efthymios A (2019) Carotid Artery Disease in Diabetic Patients: Contemporary Perspectives. J Blood Lymph 9: 238. doi: 10.4172/2165-7831.1000238
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