J. Guan, Z. Chen, H. Zhu
{"title":"新型冠状病毒与干扰素I的相互作用","authors":"J. Guan, Z. Chen, H. Zhu","doi":"10.3760/cma.j.issn.1674-2397.2021.02.004","DOIUrl":null,"url":null,"abstract":"COVID-19 has swept across the world, causing widespread epidemics and millions of life lost worldwide. After infected with 2019-nCoV, the body quickly mobilizes the innate immune response and produces type Ⅰ interferon (IFN-Ⅰ). IFN-Ⅰ plays an important role in virus clearance in the early stage of disease. This article reviews the innate immune recognition after virus infection and the interaction between 2019-nCoV and IFN-Ⅰ, which would be conductive to understanding the pathogenesis and antiviral treatment of COVID-19. © 2021 Chinese Medical Association","PeriodicalId":52394,"journal":{"name":"中华临床感染病杂志","volume":"14 1","pages":"97-101"},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The interaction between 2019-nCoV and interferon I\",\"authors\":\"J. Guan, Z. Chen, H. Zhu\",\"doi\":\"10.3760/cma.j.issn.1674-2397.2021.02.004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"COVID-19 has swept across the world, causing widespread epidemics and millions of life lost worldwide. After infected with 2019-nCoV, the body quickly mobilizes the innate immune response and produces type Ⅰ interferon (IFN-Ⅰ). IFN-Ⅰ plays an important role in virus clearance in the early stage of disease. This article reviews the innate immune recognition after virus infection and the interaction between 2019-nCoV and IFN-Ⅰ, which would be conductive to understanding the pathogenesis and antiviral treatment of COVID-19. © 2021 Chinese Medical Association\",\"PeriodicalId\":52394,\"journal\":{\"name\":\"中华临床感染病杂志\",\"volume\":\"14 1\",\"pages\":\"97-101\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中华临床感染病杂志\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3760/cma.j.issn.1674-2397.2021.02.004\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华临床感染病杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/cma.j.issn.1674-2397.2021.02.004","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
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