帕金森和干细胞治疗

Gerry Gunawan, M. Dalhar, S. Kurniawan
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引用次数: 6

摘要

帕金森病是一种神经退行性疾病,在运动或运动控制方面表现为进行性。这种疾病常发生在60岁以上的人群中。帕金森病的病因是遗传和环境因素共同作用的结果。由于总体预期寿命增加,未来患帕金森病的人数将会增加。帕金森病的治疗可采用药物治疗和非药物治疗。药物治疗可采用左旋多巴、单胺氧化酶b抑制剂、多巴胺激动剂、抗胆碱能药、金刚烷胺等,非药物治疗可采用干细胞治疗的方法。干细胞是具有两个重要特征的主细胞,它们可以通过细胞分裂进行自我更新,并可以被诱导成为具有特定功能的细胞。干细胞治疗帕金森病的目的是取代受损的多巴胺能细胞。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
PARKINSON AND STEM CELL THERAPY
Parkinson's disease is a neurodegenerative disorder that is progressive about the movement or control of movement. The disease often occurs in people over the age of 60 years. The etiology of Parkinson's disease caused by a combination of genetic and environmental factors. Because overall life expectancy increases, the number of people with Parkinson's disease will increase in the future. Treatment of Parkinson's disease can be used with pharmacological therapy and nonpharmacological therapy. Pharmacological therapy can use levodopa, monoamine oxidase-B inhibitors, dopamine agonists, anticholinergics and amantadine, while nonpharmacological therapies may use the method of stem cell therapy. Stem cells are master cells that have two important characteristics that can perform self-renewing through cell division and can be induced to become cells with specific functions. The aim of Stem cell therapy in Parkinson's disease to replace the damaged dopaminergic cells.
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