蔓越莓多酚对致龋菌的抑制作用。

IF 0.5 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Bulletin of Tokyo Dental College Pub Date : 2008-08-01 DOI:10.2209/TDCPUBLICATION.49.107

Ayumi Yamanaka-Okada, E. Sato, T. Kouchi, R. Kimizuka, Tetsuo Kato, K. Okuda

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引用次数: 51

摘要

本研究旨在探讨蔓越莓多酚提取物对变形链球菌的作用。疏水性是细菌附着在牙齿表面的一个重要因素。我们发现蔓越莓多酚组分显著降低了sobrinus 6715、Streptococcus mutans MT8148R和JC2的疏水性，且呈剂量依赖性(p<0.05)。100 μ g/ml蔓越莓多酚组分对S. sobrinus 6715和S. mutans MT8148R的生物膜形成有抑制作用(p<0.01)。当剂量增加到500 μ g/ml时，变形链球菌JC2的生物膜形成受到显著抑制(p<0.05)。500 μ g/ml蔓越莓多酚组分对变形链球菌MT8148R的生长有抑制作用(p<0.05)。

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Inhibitory effect of cranberry polyphenol on cariogenic bacteria.

The purpose of this study was to investigate the effect of cranberry polyphenol fraction on mutans streptococci. Hydrophobicity is an important factor in the adherence of bacteria to the tooth surface. We found that cranberry polyphenol fraction significantly decreased the hydrophobicity of Streptococcus sobrinus 6715, Streptococcus mutans MT8148R and JC2 in a dose-dependent manner (p<0.05). Biofilm formation by S. sobrinus 6715 and S. mutans MT8148R was inhibited by 100 microg/ml cranberry polyphenol fraction (p<0.01). When dosage was increased to 500 microg/ml, biofilm formation by S. mutans JC2 was significantly inhibited (p<0.05). Addition of 500 microg/ml cranberry polyphenol fraction to medium inhibited growth of S. mutans MT8148R compared with the control (p<0.05).

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来源期刊

Bulletin of Tokyo Dental College DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

0.90

自引率

0.00%

发文量

期刊介绍： The bulletin of Tokyo Dental collegue is principally for the publication of original contributions to multidisciplinary research in dentistry.