Elaheh Madadi Hiyagh, Sah, M. Ravasan, F. Darvishi, A. Mokhtarzadeh, B. Baradaran
{"title":"l -谷氨酰胺酶对急性淋巴细胞白血病(Raji)、乳腺癌(MCF7)和结直肠癌(A549)细胞系的抗癌作用","authors":"Elaheh Madadi Hiyagh, Sah, M. Ravasan, F. Darvishi, A. Mokhtarzadeh, B. Baradaran","doi":"10.21767/2254-6081-C1-021","DOIUrl":null,"url":null,"abstract":"Cancer Science & Pediatrics 2019 Background: There are lots of treatments for cancer but always enzymes are the most efficient. Glutamine can be used to support proliferation in multiple ways. It is a proteinogenic amino acid, and can be act as a nitrogen donor for the synthesis of amino acids as well as nucleotides biosynthesis in cellular processes. The presence of L-glutaminase has been reported in various organisms, including animals, plants, and microorganisms except humans. It’s a treatment enzyme for ALL and L-glutaminase also has proved ineffectual for treatment solid tumours such as breast cancer and colorectal. In following research Yarrowia yeast glutaminase is used.","PeriodicalId":91204,"journal":{"name":"Archives in cancer research","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Anti-cancer effect of L-Glutaminase on acute lymphoblastic leukemia (Raji), breast cancer (MCF7) and colorectal cancer (A549) cell lines\",\"authors\":\"Elaheh Madadi Hiyagh, Sah, M. Ravasan, F. Darvishi, A. Mokhtarzadeh, B. Baradaran\",\"doi\":\"10.21767/2254-6081-C1-021\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Cancer Science & Pediatrics 2019 Background: There are lots of treatments for cancer but always enzymes are the most efficient. Glutamine can be used to support proliferation in multiple ways. It is a proteinogenic amino acid, and can be act as a nitrogen donor for the synthesis of amino acids as well as nucleotides biosynthesis in cellular processes. The presence of L-glutaminase has been reported in various organisms, including animals, plants, and microorganisms except humans. It’s a treatment enzyme for ALL and L-glutaminase also has proved ineffectual for treatment solid tumours such as breast cancer and colorectal. In following research Yarrowia yeast glutaminase is used.\",\"PeriodicalId\":91204,\"journal\":{\"name\":\"Archives in cancer research\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-03-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archives in cancer research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.21767/2254-6081-C1-021\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives in cancer research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21767/2254-6081-C1-021","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Anti-cancer effect of L-Glutaminase on acute lymphoblastic leukemia (Raji), breast cancer (MCF7) and colorectal cancer (A549) cell lines
Cancer Science & Pediatrics 2019 Background: There are lots of treatments for cancer but always enzymes are the most efficient. Glutamine can be used to support proliferation in multiple ways. It is a proteinogenic amino acid, and can be act as a nitrogen donor for the synthesis of amino acids as well as nucleotides biosynthesis in cellular processes. The presence of L-glutaminase has been reported in various organisms, including animals, plants, and microorganisms except humans. It’s a treatment enzyme for ALL and L-glutaminase also has proved ineffectual for treatment solid tumours such as breast cancer and colorectal. In following research Yarrowia yeast glutaminase is used.
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