动脉粥样硬化的新危险因素

Q3 Medicine

Open Biomarkers Journal Pub Date : 2008-12-05 DOI:10.2174/1875318300801010036

A. Papazafiropoulou, N. Katsilambros, N. Tentolouris

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引用次数: 4

摘要

流行病学研究表明，经典的心血管危险因素只能解释心血管发病率和死亡率增加的一部分原因。大量研究表明，新的心血管危险因素，包括血浆同型半胱氨酸、纤维蛋白原、c反应蛋白、尿酸水平升高、白细胞计数增加以及低脂联素水平，可能在心血管疾病的发病机制中起关键作用。本文回顾了最近关于新的危险因素对健康受试者和心血管高危受试者心血管发病率和死亡率影响的文献数据。此外，本文还讨论了这些新的危险因素与动脉粥样硬化的发病机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Novel Risk Factors for Atherosclerosis~!2008-08-22~!2008-11-09~!2008-12-05~!

Epidemiologic studies demonstrated that the classical cardiovascular risk factors explain only a part of the in- creased cardiovascular morbidity and mortality. Large scale studies have shown that novel cardiovascular risk factors, in- cluding increased plasma homocysteine, fibrinogen, C-reactive protein, uric acid levels, and increased white blood cells count as well as low adiponectin levels, might have a key role in the pathogenesis of the cardiovascular disease. This re- view examines recent literature data on the effect of novel risk factors on cardiovascular morbidity and mortality in healthy subjects as well as in subjects at high cardiovascular risk. In addition, the pathogenetic mechanisms linking the ef- fects of the novel risk factors with atherosclerosis are discussed.

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来源期刊

Open Biomarkers Journal Medicine-Medicine (miscellaneous)

CiteScore

0.80

自引率

0.00%

发文量

期刊介绍： The Open Biomarkers Journal is an Open Access online journal, which publishes original full-length, short research articles and reviews on biomarkers in clinical, medical and pharmaceutical research. The coverage includes biomarkers of disease, new biomarkers, exposure to drugs, genetic effects, and applications of biomarkers. The Open Biomarkers Journal, a peer reviewed journal, aims to provide the most complete and reliable source of information on current developments in the field. The emphasis will be on publishing quality articles rapidly and freely available to researchers worldwide.