阿苯达唑和帕罗霉素治疗小牛天然贾第鞭毛虫感染的效果

IF 0.4 4区农林科学 Q4 VETERINARY SCIENCES

Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice Pub Date : 2023-01-01 DOI:10.21521/mw.6795

Onur Köse, R. Kiyici, M. Pala, R. Adanir, B. K. Karaayvaz, M. Karaca, H. A. Akkan

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引用次数: 0

摘要

本研究的目的是评估和比较阿苯达唑和帕罗霉素治疗对小牛天然贾第鞭毛虫感染的效果。这些小牛被分成两组，每组6只，每组有相似的贾第鞭毛虫寄生负荷。囊肿。A组和P组分别口服阿苯达唑(20 mg/kg)和帕罗霉素(50 mg/kg)，连续3 d。通过分析第0、3、7、10、14、21和28天的自然粪便检查中囊肿排泄的减少情况来评价药物的有效性。此外，评估第3、7、10、14、21和28天与第0天相比的减少百分比。两组粪便囊肿排出量几何平均值从第3天开始下降，帕罗霉素组从第3天开始持续下降，阿苯达唑组在第7天囊肿量增加后又下降。P组和A组在第21天和第28天，所有动物的囊肿排泄量均为零。帕罗霉素组在第3天降低率高达47.72%，第21天达到100%。阿苯达唑组第3天降低率为35.29%，第28天达到100%。结果发现，在平均囊肿减少的规律性和囊肿排泄达到零所需的时间方面，帕罗霉素比阿苯达唑更有效。

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Efficiacy of albendazole and paromomycin treatments against natural Giardia spp. infection in calves

The aim of the present study was to evaluate and compare the efficiacy of albendazole and paromomycine treatments against natural Giardia spp. infection in calves. The calves were divided in two groups of six animals each with similar parasitic loads of Giardiaspp. cysts. Albendazole (20 mg/kg) and paromomycin (50 mg/kg) were administrated orally to group A and group P, respectively, for three consecutive days. The efficiacies of drugs evaluated by analyzing the reduction in cyst excretion in native fecal examinations on days 0, 3, 7, 10, 14, 21 and 28. In addition, percentages of reduction for days 3, 7, 10, 14, 21 and 28 according to day 0 were evaluated. The geometric mean of fecal cyst excretion in both groups started to decrease from the 3rd day, in paromomycin group the decrease continued steadily throughout the examination days starting from the 3rd day, despite that in the albendazole group the cyst amount increased in the 7th day and then decreased again. Cyst excretion reached zero in all animals at the 21st and 28th days in group P and group A, respectively. The percentage of reduction started with a high rate of 47.72% on the third day and reached 100% on the 21st day in the paromomycin group. In the albendazole group, the percentage of reduction started with a rate of 35.29% on the third day and reached 100% on the 28th day. As a result, paromomycin was found to be more effective compared to albendazole in terms of both the regularity of the mean cyst reduction and the time it takes for the cyst excretion to reach zero.

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来源期刊

Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice VETERINARY SCIENCES-

CiteScore

0.80

自引率

0.00%

发文量

审稿时长

4-8 weeks

期刊介绍： "Medycyna Weterynaryjna" publishes various types of articles which are grouped in the following editorial categories: reviews, original studies, scientific and professional problems, the history of veterinary medicine, posthumous memoirs, as well as chronicles that briefly relate scientific advances and developments in the veterinary profession and medicine. The most important are the first two categories, which are published with short summaries in English. Moreover, from 2001 the editors of "Medycyna Weterynaryjna", bearing in mind market demands, has also started publishing entire works in English. Since 2008 the periodical has appeared in an electronic version. The following are available in this version: summaries of studies published from 1999 to 2005, full versions of all the studies published in the years 2006-2011 (in pdf files), and full versions of the English studies published in the current year (pdf). Only summaries of the remaining studies from the current year are available. In accordance with the principles accepted by the editors, the full versions of these texts will not be made available until next year. All articles are evaluated twice by leading Polish scientists and professionals before they are considered for publication. For years now "Medycyna Weterynaryjna" has maintained a high standard thanks to this system. The review articles are actually succinct monographs dealing with specific scientific and professional problems that are based on the most recent findings. Original works have a particular value, since they present research carried out in Polish and international scientific centers.