川崎病:是时候改变了

E. Strehle
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引用次数: 1

摘要

第一例粘膜皮肤淋巴结综合征(MLNS)是由Tomisaku Kawasaki博士于1967年报道的。他的姓氏后来被指定为这种新的疾病实体,我很幸运地在2004年柏林举行的德国儿科协会100年会议上见到了他。根据我们目前的了解川崎病(KD)是一种发生在遗传易感人群急性感染后的系统性自身免疫性血管炎。在日本以外,KD发病率低,由于与常见的儿童传染性疾病相似,而且缺乏特异性和敏感性的实验室检测,因此诊断起来非常困难。Bangert等人的病例报告[b]恰当地说明了这些困难,并呼吁及时诊断和治疗,以避免严重的心血管并发症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Kawasaki Disease: Time for Change
The first cases of mucocutaneous lymph node syndrome (MLNS) were reported by Dr Tomisaku Kawasaki in 1967. His surname was later assigned to this new disease entity, and I was fortunate to meet him at the 100 Annual Conference of the German Paediatric Association in Berlin in 2004 [1]. According to our current understanding Kawasaki disease (KD) is a systemic autoimmune vasculitis which occurs in genetically susceptible people following an acute infection. Outside Japan KD has a low incidence and is notoriously difficult to diagnose because of its similarity to common infective childhood illnesses and a lack of specific and sensitive laboratory tests. The case report of KD by Bangert et al. [2] illustrates these difficulties aptly and calls for prompt diagnosis and treatment of this condition to avoid serious cardiovascular complications.
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