外伤性心包炎牛心脏生物标志物和生化变化

IF 0.4 4区 农林科学 Q4 VETERINARY SCIENCES
C. Ayvazoğlu, E. Akyüz, M. Öğün
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引用次数: 0

摘要

外伤性心包炎(TP)的出现是由于异物刺穿心脏,这些动物无法治疗。外伤性心包炎是最重要的心脏疾病之一,可导致产奶量下降、动物死亡和妊娠动物胎儿死亡,并造成经济损失。心脏标记物已经在人类医学中使用多年,最近开始在兽医学中使用,它可以检测可能发生在心脏相关疾病早期阶段的轻微心肌损伤。本研究旨在通过心脏生物标志物测定TP牛的心脏损伤。在本研究中,TP病牛的ctn - 1、ANP、NT-proBNP、同型半胱氨酸、CRP、CK-MB、LDH、AST和ALT水平均高于健康动物(P < 0.01)。TP患者NT-proBNP升高约11倍,ANP升高约10倍,ctn - 1和同型半胱氨酸升高3倍,CRP和CK-MB升高2倍。综上所述,对一些心脏标志物进行了检测,有助于TP牛心脏损伤的早期发现和诊断,这些标志物的使用是有益的。ANP、Nt-proBNP和同型半胱氨酸是TP牛的第一批数据,可用于检测心脏损伤的严重程度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cardiac Biomarkers and Biochemical Changes in Cattle with Traumatic Pericarditis
Traumatic pericarditis (TP) emerges as a result of foreign bodies pricking the heart, and these animals cannot be treated. Traumatic pericarditis is one of the most important cardiac diseases that may result in a decrease in milk yield, animal death, and fetal deaths in affected pregnant animals and lead to economic losses. Cardiac markers, which have been used in human medicine for years and have recently started to be used in veterinary medicine, can detect mild myocardial damage that may occur in the early stages of heart-related diseases. In this study it was aimed to determine the cardiac damage in cattle with TP by cardiac biomarkers. In the study, cTn-I, ANP, NT-proBNP, homocysteine, CRP, CK-MB, LDH, AST, and ALT levels were determined to be statistically higher in cattle with TP than in healthy animals (P < 0.01). NT-proBNP increased approximately 11 times, ANP about 10 times, cTn-I and Homocysteine increased 3 times, and CRP and CK-MB increased 2 times in cattle with TP. In conclusion, some cardiac markers were examined in the early detection of cardiac damage and diagnosis of cattle with TP, and it was concluded that the use of these markers would be beneficial. Moreover, it was concluded that ANP, Nt-proBNP, and homocysteine, which were the first data on cattle with TP, could be used in the detection of the severity of cardiac damage.
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来源期刊
CiteScore
0.80
自引率
0.00%
发文量
73
审稿时长
4-8 weeks
期刊介绍: "Medycyna Weterynaryjna" publishes various types of articles which are grouped in the following editorial categories: reviews, original studies, scientific and professional problems, the history of veterinary medicine, posthumous memoirs, as well as chronicles that briefly relate scientific advances and developments in the veterinary profession and medicine. The most important are the first two categories, which are published with short summaries in English. Moreover, from 2001 the editors of "Medycyna Weterynaryjna", bearing in mind market demands, has also started publishing entire works in English. Since 2008 the periodical has appeared in an electronic version. The following are available in this version: summaries of studies published from 1999 to 2005, full versions of all the studies published in the years 2006-2011 (in pdf files), and full versions of the English studies published in the current year (pdf). Only summaries of the remaining studies from the current year are available. In accordance with the principles accepted by the editors, the full versions of these texts will not be made available until next year. All articles are evaluated twice by leading Polish scientists and professionals before they are considered for publication. For years now "Medycyna Weterynaryjna" has maintained a high standard thanks to this system. The review articles are actually succinct monographs dealing with specific scientific and professional problems that are based on the most recent findings. Original works have a particular value, since they present research carried out in Polish and international scientific centers.
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