C. Cras-Méneur, L. Elghazi, Bo Ye, M. Blandino-Rosano, Ernesto Bernal-MiIzrachi
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The Tuberous Sclerosis complex (TSC) integrates metabolic and growth signals. Recent data demonstrate that this pathway is a major player in regulation of metabolism and energy balance. In this review, we will focus on the role of TSC in modulation of -cell mass and function.