基于聚D，L-丙交酯-CO-GLICOLIDE的微胶囊阿普唑仑的稳定性研究及有效期

IF 0.5 Q4 PHARMACOLOGY & PHARMACY

Pharmacy & Pharmacology-Farmatsiya i Farmakologiya Pub Date : 2015-09-12 DOI:10.19163/2307-9266-2014-2-4(5)-63-70

Александр Игоревич Медвецкий, Лидия Ильинична Щербакова, Владислав Алексеевич Компанцев, Л. П. Гокжаева, Т. М. Васина

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引用次数: 0

摘要

采用“加速老化”法研究了阿普唑仑微颗粒在自然条件下的稳定性。结果表明，在研究过程中，阿普唑仑的微粒没有受到破坏，其外观也没有改变。采用范霍夫公式计算了阿普唑仑微粒测定的有效期。有效期定为2年。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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ИЗУЧЕНИЕ СТАБИЛЬНОСТИ И УСТАНОВЛЕНИЕ СРОКОВ ГОДНОСТИ МИКРОЧАСТИЦ АЛПРАЗОЛАМА НА ОСНОВЕ ПОЛИ-D,L-ЛАКТИД-КО-ГЛИКОЛИДА

Stability of microparticles of alprazolam in natural conditions was studied by the method of "accelerated aging". It was established that microparticles of alprazolam were not exposed to disruption and their appearance was not altered during the research. Expiration dates of alprazolam microparticles determination was calculated using the formula of J.H. van't Hoff. The expiration date made 2 years.

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来源期刊

Pharmacy & Pharmacology-Farmatsiya i Farmakologiya PHARMACOLOGY & PHARMACY-

CiteScore

1.10

自引率

16.70%

发文量

审稿时长

8 weeks