A. Annunziata, A. Coppola, M. Lanza, Francecsa Simioli, P. Imitazione, N. Pepe, V. Maddaloni, L. Atripaldi, G. Fiorentino
{"title":"重症COVID-19的ACE DD多态性","authors":"A. Annunziata, A. Coppola, M. Lanza, Francecsa Simioli, P. Imitazione, N. Pepe, V. Maddaloni, L. Atripaldi, G. Fiorentino","doi":"10.15761/JTS.1000396","DOIUrl":null,"url":null,"abstract":"The insertion/deletion polymorphism of the angiotensin converting enzyme (ACE) gene, previously described in association with adult respiratory distress syndrome, may play a key role in lung injury in patients with SARS-COV2. In this paper we describe 26 patients with severe respiratory failure related to COVID-19 pneumonia that underwent genetic screening for ACE polymorphisms.","PeriodicalId":74000,"journal":{"name":"Journal of translational science","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":"{\"title\":\"ACE DD polymorphism in severe COVID-19\",\"authors\":\"A. Annunziata, A. Coppola, M. Lanza, Francecsa Simioli, P. Imitazione, N. Pepe, V. Maddaloni, L. Atripaldi, G. Fiorentino\",\"doi\":\"10.15761/JTS.1000396\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The insertion/deletion polymorphism of the angiotensin converting enzyme (ACE) gene, previously described in association with adult respiratory distress syndrome, may play a key role in lung injury in patients with SARS-COV2. In this paper we describe 26 patients with severe respiratory failure related to COVID-19 pneumonia that underwent genetic screening for ACE polymorphisms.\",\"PeriodicalId\":74000,\"journal\":{\"name\":\"Journal of translational science\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of translational science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15761/JTS.1000396\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of translational science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15761/JTS.1000396","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The insertion/deletion polymorphism of the angiotensin converting enzyme (ACE) gene, previously described in association with adult respiratory distress syndrome, may play a key role in lung injury in patients with SARS-COV2. In this paper we describe 26 patients with severe respiratory failure related to COVID-19 pneumonia that underwent genetic screening for ACE polymorphisms.