儿童脊髓真皮窦并发症:病例系列及文献回顾

Q4 Medicine
D. Forlino, P. Manzone, D. Ebel, Romilio Monzón, Hugo Marcelo Wirz
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引用次数: 0

摘要

摘要简介:真皮窦(DS)是一种罕见的畸形。它可以是无症状的,被感染,并产生严重的神经系统症状。我们的目的是报道一系列小儿脊髓退行性椎体滑移合并感染(DSCI)的病例,描述死产的解剖结果,以及相关病理和治疗方法。方法:对5例脊髓性脊髓损伤患儿的临床病史进行分析。此外,解剖解剖死胎腰椎退行性椎体滑移进行了。结果:包括2名男性和3名女性,平均年龄2岁零9个月:2名腰椎(1名在中线,另一名在正中区),1名在胸区,1名在上颈区,1名在腰骶区。表现形式为3种脑膜特征(一种伴有疼痛和局部肿胀)和3种神经功能缺损(一种与脑膜特征有关,另一种与疼痛和肿瘤有关)。在所有病例中,通过磁共振成像(MRI)确定了DS的束。相关病变包括1例脊背髓内皮样囊肿,1例脊髓栓系伴脊髓空洞,1例部分颈髓断裂,2例脊柱发育异常。其中4人接受手术,1人在手术前死于感染并发症。在12周大的男性腰椎退行性椎体滑移胎儿中,证实了蛛网膜下腔的可渗透通道。结论:应结合MRI对dsciso进行研究,以确定其束,中枢神经系统的感染性并发症,相关畸形,包涵性肿瘤,并进行鉴别诊断。一旦确诊,应立即进行手术和长期抗生素治疗。证据水平IV;治疗研究(治疗结果调查)
本文章由计算机程序翻译,如有差异,请以英文原文为准。
SPINAL DERMAL SINUS COMPLICATION IN CHILDREN: CASE SERIES AND LITERATURE REVIEW
ABSTRACT Introduction: Dermal sinus (DS) is a rare dysraphism. It can be asymptomatic, become infected, and produce severe neurological symptoms. Our objective is to present a series of pediatric cases with spinal DS complicated byinfections (DSCI), describe the findings correlated with the anatomy in a stillbirth, as well as the associated pathologies and their treatment. Method: We analyzeddifferent variables in the clinical histories of 5 children with spinal DSCI. In addition, an anatomical dissection of a stillbirth with lumbar DS was performed. Results: Two males and 3 femaleswith DSCI and a mean age of 2 years and 9 months were included: 2 lumbar (one in the midline and the other in theparamedian region), 1 in the thoracic region, 1 in the upper cervical region,and 1 in the lumbosacral region. The forms of presentation were 3 meningeal profiles (one with pain andlocalized swelling) and 3 neurological deficits (one associated with the meningeal profile and another associated with pain and a tumor). In all cases, the tract of the DS was identified by magnetic resonance imaging (MRI).Associated lesions included 1 dorsal intramedullary dermoid cyst, 1 tethered lumbar spinal cord with syringomyelia, 1 partial cervical medullary disconnection, and 2 spinal dysraphisms. Four were operated on and one died of infectious complications before surgery. In the 12-week-old male fetus with lumbar DS, a permeable tract to the subarachnoid space was verified. Conclusions: DSCIsshould bestudied with MRI to identify their tracts, infectious complications of thecentral nervous system, associated malformations, inclusion tumors, and to enabledifferential diagnosis. Once diagnosed, they should be urgently treated both surgically and with prolonged antibiotictherapy. Level of Evidence IV; Therapeutic Study (Treatment Outcome Investigation)
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来源期刊
Coluna/ Columna
Coluna/ Columna Medicine-Surgery
CiteScore
0.40
自引率
0.00%
发文量
32
审稿时长
10 weeks
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