下丘脑血运重建与年轻化

H. Rafael, M. T. Valadez
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引用次数: 4

摘要

背景:自1990年至今,已有四种治疗衰老的方法。所有这些都能提高血浆生长激素水平。材料与方法:选择38例患者进行术后年轻化分析。在此之前,所有患者都在视交叉、颈动脉分叉和前穿孔间隙接受了网膜移植。脑卒中14例,阿尔茨海默病(AD) 23例,亨廷顿病(HD) 1例。通过观察、录像、摄影等方法获得复壮的临床资料。结果:卒中、AD和HD患者的神经系统改善在手术后的头几周比接下来的几个月或几年更好。术后1 ~ 4个月,32例(84.21%)出现年轻化,其余无变化。最后6例患者表现为第三脑室扩张。结论:这些结果表明衰老的主要原因是下丘脑弓状核的缺血起源。因为,与此相反,它的血运重建通过大网膜组织产生年轻化。因此,我们的手术方法改善了残余弓状核和邻近区域的功能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Hypothalamic Revascularization and Rejuvenation 
Background: Since 1990 and to date, four therapeutic methods have been used against aging. All of them, to increase the plasma growth hormone levels.  Material and Method: We choose 38 patients to analyse the postoperative rejuvenation. Previously, all of them have been received omental transplantation on the optic chiasma, the carotid bifurcation and the anterior perforated space. Patients with stroke in 14 cases, Alzheimer´s disease (AD) in 23 and Huntington´s disease (HD) in 1. The clinical data of rejuvenation were obtained by observation, videotape and photography.  Results: Neurological improvement in patients with stroke, AD and HD were better during the first weeks after surgery than in the following months or years. Besides this, between 1 to 4 months after surgery, 32 patients (84.21%) showed rejuvenation and in the rest, there were not changes. These 6 last patients presented dilation of the third ventricle.  Conclusions: These results indicate that the primary cause of aging is of ischemic origin, in the arcuate nucleus of the hypothalamus. Because, in contrast to this, its revascularization by means of omental tissue produce rejuvenation. Therefore, our surgical method improve the function of the residual arcuate nucleus and adjacent zones. 
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