{"title":"动物模型:渡边遗传性高脂血症兔","authors":"B. J. Lenten","doi":"10.1159/000416892","DOIUrl":null,"url":null,"abstract":"An exciting animal model has become available that closely resembles human FH. Named after the investigator who first developed the strain, the Watanabe Heritable Hyperlipidemic (WHHL) rabbit has markedly elevated plasma cholesterol levels and spontaneously develops atherosclerosis and tissue xanthoma","PeriodicalId":76182,"journal":{"name":"Monographs in human genetics","volume":"12 1","pages":"125-138"},"PeriodicalIF":0.0000,"publicationDate":"1989-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000416892","citationCount":"3","resultStr":"{\"title\":\"Animal Models: The Watanabe Heritable Hyperlipidemic Rabbit\",\"authors\":\"B. J. Lenten\",\"doi\":\"10.1159/000416892\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"An exciting animal model has become available that closely resembles human FH. Named after the investigator who first developed the strain, the Watanabe Heritable Hyperlipidemic (WHHL) rabbit has markedly elevated plasma cholesterol levels and spontaneously develops atherosclerosis and tissue xanthoma\",\"PeriodicalId\":76182,\"journal\":{\"name\":\"Monographs in human genetics\",\"volume\":\"12 1\",\"pages\":\"125-138\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1989-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1159/000416892\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Monographs in human genetics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1159/000416892\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Monographs in human genetics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000416892","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Animal Models: The Watanabe Heritable Hyperlipidemic Rabbit
An exciting animal model has become available that closely resembles human FH. Named after the investigator who first developed the strain, the Watanabe Heritable Hyperlipidemic (WHHL) rabbit has markedly elevated plasma cholesterol levels and spontaneously develops atherosclerosis and tissue xanthoma
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