多重耐药和广泛耐药细菌的研究

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2016-01-28 DOI:10.1155/2016/4065603

S. Basak, Priyanka Singh, Monali N. Rajurkar

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引用次数: 242

摘要

背景和目的。抗微生物药物耐药性现在是临床医生治疗患者的主要挑战。因此，进行了这项短期研究，以检测三级保健医院中多重耐药(MDR)、广泛耐药(XDR)和普遍耐药(PDR)细菌分离株的发生率。材料和方法。临床标本在微生物科进行培养和菌种鉴定。研究不同菌株的药敏谱，检测MDR、XDR和PDR细菌。结果。对1060株细菌的药敏谱进行了研究。MDR 393株(37.1%)，XDR 146株(13.8%)，未分离到PDR。所有(100%)革兰氏阴性菌株对粘菌素敏感，而所有(100%)革兰氏阳性菌株对万古霉素敏感。结论。所有临床微生物实验室都必须密切监测耐多药、广泛耐药甚至PDR，以实施有效措施，减少抗菌素耐药性的威胁。

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Multidrug Resistant and Extensively Drug Resistant Bacteria: A Study

Background and Objective. Antimicrobial resistance is now a major challenge to clinicians for treating patients. Hence, this short term study was undertaken to detect the incidence of multidrug-resistant (MDR), extensively drug-resistant (XDR), and pandrug-resistant (PDR) bacterial isolates in a tertiary care hospital. Material and Methods. The clinical samples were cultured and bacterial strains were identified in the department of microbiology. The antibiotic susceptibility profile of different bacterial isolates was studied to detect MDR, XDR, and PDR bacteria. Results. The antibiotic susceptibility profile of 1060 bacterial strains was studied. 393 (37.1%) bacterial strains were MDR, 146 (13.8%) strains were XDR, and no PDR was isolated. All (100%) Gram negative bacterial strains were sensitive to colistin whereas all (100%) Gram positive bacterial strains were sensitive to vancomycin. Conclusion. Close monitoring of MDR, XDR, or even PDR must be done by all clinical microbiology laboratories to implement effective measures to reduce the menace of antimicrobial resistance.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.