疼痛的神经生物学。

Advances in Psychosomatic Medicine Pub Date : 2006-12-01 DOI:10.1159/000095367

M. Clark, G. Treisman

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引用次数: 273

摘要

疼痛的神经生物学已经进行了广泛的研究，旨在确定伤害性传递和整合的机制。如果不了解疼痛调节的复杂机制，包括幻肢痛在内的慢性疼痛的临床状况是无法解释的。概述了痛觉系统的神经生物学组织，从不同的疼痛纤维类型到皮层下和皮层体验中心，并简要描述了系统内以及疼痛通路与其他信息通路之间的已知串扰。最后，简要描述了情感、执行和认知过程与疼痛体验之间的相互作用。

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Neurobiology of pain.

The neurobiology of pain has had extensive research directed at identifying the mechanisms of nociceptive transmission and integration. Clinical conditions of chronic pain including phantom limb pain cannot be explained without an understanding of the complex mechanisms of pain regulation. An overview of the neurobiological organization of the nociceptive system, from different pain fiber types to subcortical and cortical experiential centers, is presented, along with a brief description of the known cross talk within the system and between pain pathways and those for other information. Finally, interactions between affective, executive, and cognitive processes and pain experiences are described briefly.

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来源期刊

Advances in Psychosomatic Medicine

自引率

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发文量

期刊介绍： The importance of psychosomatic research has been greatly reinforced by evidence demonstrating that psychological phenomena may have distinct effects on human health. Recognizing the complexity of interactions between personality and physical illness, this series employs an interdisciplinary strategy to explore areas where knowledge from psychosomatic medicine may aid in the prevention of specific diseases or help meet the emotional demands of hospitalized patients. In each work, the editor has managed to bring together distinguished contributors, creating a series of coherent and comprehensive reviews on a variety of novel topics.