迟发性产科瘫痪修复中的神经移植

IF 1.1 Q4 CLINICAL NEUROLOGY
F. Senes, N. Catena, J. Senes
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引用次数: 6

摘要

摘要目的产科臂丛神经麻痹(OBPP)患儿发现神经根撕脱后,一期臂丛神经修复通常采用不同神经干的神经化手术,利用健康的神经结构远端连接上肢神经。本文旨在概述我们在OBPP中神经化手术的经验,其中包括在初次修复未发生或失败的情况下延迟修复的神经转移。此外,我们建议有机会进行后期修复,重点是延长神经手术的时间限制,超出通常推荐的时间。虽然,根据不同作者的说法,时间限制仍不清楚,但一般估计神经修复应该在出生后的头几个月内进行。事实上,显微外科手术修复OBPP是幼童的首选技术,否则会有不利的结果。然而,在某些情况下,恢复过程并不明确,因此并非所有患者都适合进行原发性神经手术。方法在2005年1月至2011年1月期间,在105例OBPP患者中,年龄从1个月到7岁,作者确定了32例部分恢复的患者。所有患者都接受了选择性神经化手术,手术时间从5个月到6.6岁不等。结果:这些患者在儿童早期表现为运动功能下降,而晚期肌群神经化治疗使其功能得到了相当大的恢复。除了5名患者外,上述患者最初会避免手术,因为他们不符合神经手术的标准。结论迟发性神经外科手术是治疗儿童OBPP的有效方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nerve Transfer in Delayed Obstetrical Palsy Repair
Abstract Objective When root avulsions are detected in children suffering from obstetrical brachial plexus palsy (OBPP), neurotization procedures of different nerve trunks are commonly applied in primary brachial plexus repair, to connect distally the nerves of the upper limbs using healthy nerve structures. This article aims to outline our experience of neurotization procedures in OBPP, which involves nerve transfers in the event of delayed repair, when a primary repair has not occurred or has failed. In addition, we propose the opportunity for late repair, focusing on extending the time limit for nerve surgery beyond that which is usually recommended. Although, according to different authors, the time limit is still unclear, it is generally estimated that nerve repair should take place within the first months of life. In fact, microsurgical repair of OBPP is the technique of choice for young children with the condition who would otherwise have an unfavorable outcome. However, in certain cases the recovery process is not clearly defined so not all the patients are direct candidates for primary nerve surgery. Methods In the period spanning January 2005 through January 2011, among a group of 105 patients suffering from OBPP, ranging from 1 month to 7 years of age, the authors have identified a group of 32 partially recovered patients. All these patients underwent selective neurotization surgery, which was performed in a period ranging from 5 months to 6.6 years of age. Results Late neurotization of muscular groups achieved considerable functional recovery in these patients, who presented with reduced motor function during early childhood. The said patients, with the exception of five, would initially have avoided surgery because they had not met the criteria for nerve surgery. Conclusion We have concluded that the execution of late nerve surgical procedures can be effective in children affected by OBPP.
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来源期刊
CiteScore
1.70
自引率
14.30%
发文量
6
审稿时长
12 weeks
期刊介绍: JBPPNI is an open access, peer-reviewed online journal that will encompass all aspects of basic and clinical research findings, in the area of brachial plexus and peripheral nerve injury. Injury in this context refers to congenital, inflammatory, traumatic, degenerative and neoplastic processes, including neurofibromatosis. Papers on diagnostic and imaging aspects of the peripheral nervous system are welcomed as well. The peripheral nervous system is unique in its complexity and scope of influence. There are areas of interest in the anatomy, physiology, metabolism, phylogeny, and limb growth tropism of peripheral nerves.
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