凯文·拉弗蒂和淋巴细胞共刺激剂:堪培拉的理论与实践

IF 3.2 4区医学 Q3 CELL BIOLOGY

Immunology & Cell Biology Pub Date : 2023-08-23 DOI:10.1111/imcb.12683

Philip D Hodgkin

{"title":"凯文·拉弗蒂和淋巴细胞共刺激剂:堪培拉的理论与实践","authors":"Philip D Hodgkin","doi":"10.1111/imcb.12683","DOIUrl":null,"url":null,"abstract":"Between 1969 and 1983 the lab of Kevin Lafferty in Canberra developed the concept of the T-cell “costimulator,” an essential second signal for activation. A great deal of the work appeared in this journal before it was known as Immunology & Cell Biology (ICB). As part of the 100-year anniversary of the journal, I offer a personal reflection on Kevin's legacy and impact.","PeriodicalId":179,"journal":{"name":"Immunology & Cell Biology","volume":"101 8","pages":"678-683"},"PeriodicalIF":3.2000,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/imcb.12683","citationCount":"1","resultStr":"{\"title\":\"Kevin Lafferty and the lymphocyte costimulator: theory and practice in Canberra\",\"authors\":\"Philip D Hodgkin\",\"doi\":\"10.1111/imcb.12683\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Between 1969 and 1983 the lab of Kevin Lafferty in Canberra developed the concept of the T-cell “costimulator,” an essential second signal for activation. A great deal of the work appeared in this journal before it was known as Immunology & Cell Biology (ICB). As part of the 100-year anniversary of the journal, I offer a personal reflection on Kevin's legacy and impact.\",\"PeriodicalId\":179,\"journal\":{\"name\":\"Immunology & Cell Biology\",\"volume\":\"101 8\",\"pages\":\"678-683\"},\"PeriodicalIF\":3.2000,\"publicationDate\":\"2023-08-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1111/imcb.12683\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Immunology & Cell Biology\",\"FirstCategoryId\":\"2\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/imcb.12683\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CELL BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Immunology & Cell Biology","FirstCategoryId":"2","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/imcb.12683","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CELL BIOLOGY","Score":null,"Total":0}

引用次数: 1

摘要

1969年至1983年间，堪培拉的凯文·拉弗蒂(Kevin Lafferty)实验室提出了t细胞“共刺激器”的概念，这是激活t细胞的重要第二信号。在这本杂志被称为《免疫学》之前，很多研究都发表在这本杂志上。细胞生物学(ICB)。作为该杂志100周年纪念的一部分，我对凯文的遗产和影响提出了个人的反思。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Kevin Lafferty and the lymphocyte costimulator: theory and practice in Canberra

查看原文本刊更多论文

Kevin Lafferty and the lymphocyte costimulator: theory and practice in Canberra

Between 1969 and 1983 the lab of Kevin Lafferty in Canberra developed the concept of the T-cell “costimulator,” an essential second signal for activation. A great deal of the work appeared in this journal before it was known as Immunology & Cell Biology (ICB). As part of the 100-year anniversary of the journal, I offer a personal reflection on Kevin's legacy and impact.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Immunology & Cell Biology 医学-免疫学

CiteScore

7.50

自引率

2.50%

发文量

审稿时长

4-8 weeks

期刊介绍： The Australasian Society for Immunology Incorporated (ASI) was created by the amalgamation in 1991 of the Australian Society for Immunology, formed in 1970, and the New Zealand Society for Immunology, formed in 1975. The aim of the Society is to encourage and support the discipline of immunology in the Australasian region. It is a broadly based Society, embracing clinical and experimental, cellular and molecular immunology in humans and animals. The Society provides a network for the exchange of information and for collaboration within Australia, New Zealand and overseas. ASI members have been prominent in advancing biological and medical research worldwide. We seek to encourage the study of immunology in Australia and New Zealand and are active in introducing young scientists to the discipline.