精神病学死亡率研究的方法和概念方面

A. Biggeri, D. Catelan
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引用次数: 2

摘要

大量文献记录了精神病人和普通人群之间自然原因的死亡率差异。癌症疾病的模式就不太清楚了。当试图解释这种死亡率差距时,方法学问题就出现了:选择偏差和反向因果关系;时间相关的混杂因素也是中间变量;必须考虑生命历程中的复杂关系。我们试图用因果图来解释这类问题。此外,还记录了不能归因于较高的风险因素流行率或治疗副作用的死亡原因的过度风险,以及可避免原因造成的较高死亡率。这些发现强调有必要研究针对精神病患者的健康促进和预防方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The methodological and conceptual aspects of mortality studies in psychiatry
Abstract An extensive literature documented a mortality differential for natural causes between psychiatric patients and the general population. Less clear is the pattern for cancer diseases. Methodological problems arise when trying to explain such mortality gap: selection bias and reverse causation; time-dependent confounders that are also intermediate variables; complex relationships within a life course have to be considered. We try to explain such problems in terms of causal graphs. Excess risk for causes of death which are not attributable to higher prevalence of risk factors or treatment side-effects and higher mortality rates for avoidable causes have been also documented. These findings underline the need for research on health promotion and preventive programs targeted to psychiatric patients.
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