完全失神经兔胫骨前肌的纤颤电位

Tatjana Paternostro-Sluga , M. Nuhr , Ch. Kermer , Th. Lang , A. Sabbas , V. Fialka-Moser
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摘要

本研究的目的是评估新西兰大白兔胫骨前肌完全去神经支配4个月后颤电位的定量表达和幅度,并比较量化颤电位的方法。对9只成年雌性新西兰大白兔胫骨前肌因腓神经切除而完全失神经和肌神经化而无再神经支配的情况进行了评价。组织学检查证实轴突变性和肌肉失神经支配。去神经4个月后进行针肌电图。纤维性颤动电位的定量表达通过记录每秒钟的放电率,根据整体肌肉的Daube评分和每个记录部位的修改评分进行评分来评估。每个记录点的最高振幅逐峰测量。描述性地进行统计评价,并使用Wilxocon's signet-rank检验来比较不同等级之间的射击率。59个单记录点检查失神经胫前肌。所有记录点的FPs平均发射速率为247.2±96.7脉冲/s。根据Daube评分对整体肌肉进行评分,所有肌肉的活动度均为3-4 +。根据修改后的评分对单个记录点进行评分,45.8%的记录点具有4+活性,44.1%的记录点具有3+活性,10.1%的记录点具有2+活性。本研究提供了完全失神经兔胫骨前肌纤颤电位的定量电生理数据,并提出了量化方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fibrillation potentials in completely denervated rabbit tibialis anterior muscles

The aim of the study was to assess the quantitative expression and amplitude of fibrillation potentials after 4 months of complete denervation in New Zealand White rabbit tibialis anterior muscles and to compare methods to quantify fibrillation potentials.

Nine adult female New Zealand White rabbits with completely denervated tibialis anterior muscle due to resection of the peroneal nerve and muscle nerve muscle neurotization without reinnervation were evaluated. Axonal degeneration and muscle denervation were documented by histological examination. Needle electromyography was performed after 4 months of denervation. Quantitative expression of fibrillation potentials was assessed by recording the firing rate per second, grading according to Daube's score for the overall muscle and grading according to a modified score for each recording site. The highest amplitude of each recording site was measured peak to peak. Statistical evaluation was done descriptively and Wilxocon's signet-rank test was performed to compare firing rates between different grades.

Fifty-nine single recording sites were examined for denervated tibialis anterior muscle. The mean firing rate of FPs for all recording sites was 247.2 ± 96.7 pulses/s. Grading for the overall muscle according to Daube's score showed 3–4+ activity for all muscles. Grading for single recording sites according to the modified score showed 4+ activity in 45.8% of recording sites, 3+ activity in 44,1% and 2+ activity in 10.1%.

The study provides quantitative electrophysiological data of fibrillation potentials in completely denervated rabbit tibialis anterior muscle and presents methods of quantification.

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