药物引起的止血和纤维蛋白溶解的改变

IF 2.5 3区医学 Q2 HEMATOLOGY

Hematology-Oncology Clinics of North America Pub Date : 1992-12-01 DOI:10.1016/S0889-8588(18)30272-7

Jawed Fareed PhD , Debra Hoppenstedt MS , Rodger L. Bick MD, FACP , Peter Bacher MD

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引用次数: 12

摘要

止血和纤溶系统对患者在特定临床环境下的整体病理生理状态有重要影响。这些系统的药物调节在促进治疗效果方面起着至关重要的作用，但也可能产生出血或血栓性疾病。许多药物似乎是惰性的;然而，它们可以调节止血系统和纤溶系统。然而，这种影响取决于几个因素，但足够重要，足以被认为是对患者的最佳护理。因此，建议在给药过程中对止血和纤溶系统进行常规监测。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Drug-Induced Alterations of Hemostasis and Fibrinolysis

The hemostatic and fibrinolytic systems contribute significantly to the overall pathophysiologic status of a patient in a given clinical setting. Drug modulation of these systems plays a crucial role in the facilitation of the therapeutic effects but may also produce bleeding or thrombotic disorders. Many drugs appear inert; they can, however, modulate both the hemostatic and fibrinolytic systems. Such effects depend on several factors, however, but are significant enough to be recognized for the optimal care of patients. Therefore, it is recommended that the hemostatic and fibrinolytic systems should be routinely monitored during drug delivery.

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来源期刊

Hematology-Oncology Clinics of North America 医学-血液学

CiteScore

4.10

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Hematology/Oncology Clinics updates you on the latest trends in patient management, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Under the direction of an experienced guest editor, each issue focuses on a single topic in hematology and oncology, including hemostasis and thrombosis, molecular and cellular basis of hematology, coagulation disorders, and cancers—bone, gastrointestinal, head and neck, lymphomas, neuroendocrine, breast, renal cell, melanoma, and more.