发病年龄与DSM-IV酒精滥用和依赖:12年随访

Bridget F Grant , Frederick S Stinson , Thomas C Harford
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引用次数: 574

摘要

目的:本研究的目的是在一项对美国青少年进行的为期12年的前瞻性研究中,探讨饮酒开始年龄与DSM-IV酒精滥用和依赖发展之间的关系。方法:采用Logistic回归分析,控制社会人口学因素和问题指标,量化饮酒年龄与酒精滥用和依赖发展之间的关系。结果:每推迟一年饮酒开始,1989年酒精依赖的几率下降5%,1994年下降9.0%。1994年,酒精滥用的几率随着开始饮酒年龄的逐年下降而增加7.0%,而1989年开始饮酒年龄与酒精滥用无关。1989年和1994年发现,其他几个风险因素是滥用和依赖的强烈和一致的预测因素,包括男性、离婚、分居或未婚、年轻、早期有反社会行为和大麻使用史。意义:本研究结果的意义讨论了可能影响发病-滥用和发病-依赖关系的其他因素,以及未来预防工作的重点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Age at onset of alcohol use and DSM-IV alcohol abuse and dependence: A 12-year follow-up

Purpose: The purpose of this study was to examine the relationship between age at drinking onset and the development of DSM-IV alcohol abuse and dependence in a 12-year prospective study of youth in the United States. Methods: Logistic regression analyses were used to quantify the relationship between age at drinking onset and the development of alcohol abuse and dependence controlling for sociodemographic factors and problem indicators. Results: The odds of alcohol dependence decreased by 5% in 1989 and 9.0% in 1994 for each year drinking onset was delayed. In 1994, the odds of alcohol abuse increased by 7.0% with each decreasing year of age at drinking onset, while age at drinking onset was not related to alcohol abuse in 1989. Several other risk factors were found to be strong and consistent predictors of abuse and dependence in 1989 and 1994, including being male, divorced, separated or never married, younger, and having an early history antisocial behaviors and marijuana use. Implications: Implications of the results of this study are discussed in terms of other factors that may impact on the onset-abuse and onset-dependence relationship and the need to focus future prevention efforts.

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