突触蛋白的相互作用

Signal transduction Pub Date : 2006-04-01 DOI:10.1002/SITA.200500076

E. Rosivatz

{"title":"突触蛋白的相互作用","authors":"E. Rosivatz","doi":"10.1002/SITA.200500076","DOIUrl":null,"url":null,"abstract":"Synaptojanin is a phosphoinositide phosphatase that plays a crucial role in synaptic vesicle recycling. The focus of this review is on the major direct interacting partners of synaptojanin with respect to recognition motifs in synaptojanin isoforms and splice variants. Those proteins that bind synaptojanin are mainly involved in endocytosis and function at the interface between actin and the endocytic machinery. Some interaction partners underline synaptojanin's emerging role in signaling and pathophysiological processes.","PeriodicalId":88702,"journal":{"name":"Signal transduction","volume":"101 9","pages":"101-111"},"PeriodicalIF":0.0000,"publicationDate":"2006-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/SITA.200500076","citationCount":"3","resultStr":"{\"title\":\"Interactions of synaptojanin\",\"authors\":\"E. Rosivatz\",\"doi\":\"10.1002/SITA.200500076\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Synaptojanin is a phosphoinositide phosphatase that plays a crucial role in synaptic vesicle recycling. The focus of this review is on the major direct interacting partners of synaptojanin with respect to recognition motifs in synaptojanin isoforms and splice variants. Those proteins that bind synaptojanin are mainly involved in endocytosis and function at the interface between actin and the endocytic machinery. Some interaction partners underline synaptojanin's emerging role in signaling and pathophysiological processes.\",\"PeriodicalId\":88702,\"journal\":{\"name\":\"Signal transduction\",\"volume\":\"101 9\",\"pages\":\"101-111\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2006-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1002/SITA.200500076\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Signal transduction\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1002/SITA.200500076\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Signal transduction","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/SITA.200500076","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 3

摘要

Synaptojanin是一种磷酸肌肽磷酸酶，在突触囊泡循环中起着至关重要的作用。本文综述的重点是synaptojanin的主要直接相互作用伙伴，涉及synaptojanin同工型和剪接变异体中的识别基序。这些结合突触蛋白的蛋白质主要参与内吞作用，并在肌动蛋白和内吞机制的界面上起作用。一些相互作用伙伴强调突触janin在信号传导和病理生理过程中的新兴作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Interactions of synaptojanin

Synaptojanin is a phosphoinositide phosphatase that plays a crucial role in synaptic vesicle recycling. The focus of this review is on the major direct interacting partners of synaptojanin with respect to recognition motifs in synaptojanin isoforms and splice variants. Those proteins that bind synaptojanin are mainly involved in endocytosis and function at the interface between actin and the endocytic machinery. Some interaction partners underline synaptojanin's emerging role in signaling and pathophysiological processes.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Signal transduction

自引率

0.00%

发文量