抑郁症和多发病——一项全国性研究的结果

IF 2.5 4区 医学 Q2 PSYCHIATRY
Bárbara Pedrosa , Mariana Neto , Sónia Namorado , Andreia Leite
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引用次数: 0

摘要

背景与目的关于抑郁症与慢性身体疾病之间关系的大多数研究都集中在单一的身体疾病上,没有考虑多发病或抑郁症的严重程度。考虑到慢性身体疾病的类型和数量以及抑郁症的严重程度,我们旨在描述这种关系。方法我们使用电话家庭小组的数据进行了一项横断面研究,以“慢性身体疾病”为暴露对象,以“抑郁症”为结果。样本代表葡萄牙人口。在抑郁症的存在/严重程度和慢性身体疾病的存在/类型/数量之间进行了调整后的logistic和多项式回归分析。计算可能的混杂因素调整后的比值比和95%置信区间。结果纳入1027人。在人群中,8.9%的人患有抑郁症,72.1%的人至少患有一种慢性身体疾病。抑郁症与一般身体疾病之间没有统计学上的显著关系(OR=1.68[CI95%:0.55,5.15]),但与过敏(OR=2.08[CI95%3.02,4.25])和慢性阻塞性肺病(OR=3.04[CI95%41.21,7.61])有关。两种或三种以上的身体疾病患抑郁症的风险较小(与三种以上相比,OR=0.32[CI95%20.15,0.68]),观察到过敏和更高数量的身体疾病和抑郁。临床医生应该意识到这些关系。建议评估多发病、COPD和过敏患者是否存在抑郁症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Depression and multimorbidity - Results from a nationwide study

Background and objectives

Most studies concerning the relationship between depression and chronic physical disease focused on a single physical disease and did not consider multimorbidity or depression severity. We aimed to characterize this relationship considering chronic physical diseases’ type and number, and depression severity.

Methods

We undertook a cross-sectional study, using data from a phone household panel, with “chronic physical disease” as the exposure and “depression” as the outcome. The sample is representative of the Portuguese population. Adjusted logistic and multinomial regression analyses were conducted between depression presence/severity and chronic physical disease presence/type/number. Odds ratio and 95% confidence intervals adjusted for possible confounders were calculated.

Results

1027 individuals were included. Of the population, 8.9% had depression and 72.1% had at least one chronic physical disease. There was no statistically significant relationship between depression and physical disease in general (OR=1.68 [CI95%:0.55, 5.15]), but there was with allergy (OR=2.08 [CI95%:1.02, 4.25]) and COPD (OR=3.04 [CI95%:1.21, 7.61]). The risk of depression was smaller with two physical diseases (vs. three or more, OR=0.32 [CI95%:0.15, 0.68]).

Conclusions

A relationship between COPD, allergy and a higher number of physical diseases and depression was observed. Clinicians should be aware of these relationships. Evaluating the presence of depression in people with multimorbidity, COPD and allergy is recommended.

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来源期刊
CiteScore
2.90
自引率
0.00%
发文量
40
审稿时长
43 days
期刊介绍: The European journal of psychiatry is a quarterly publication founded in 1986 and directed by Professor Seva until his death in 2004. It was originally intended to report “the scientific activity of European psychiatrists” and “to bring about a greater degree of communication” among them. However, “since scientific knowledge has no geographical or cultural boundaries, is open to contributions from all over the world”. These principles are maintained in the new stage of the journal, now expanded with the help of an American editor.
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