具有增强生物应用的新型超级纳米复合材料(CeO-SiO2纳米复合材料)的合成与表征

G. Sabeena, S. Vainath praveen, E. Pushpalakshmi, S. Rajaduraipandian, G. Annadurai
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引用次数: 0

摘要

氧化铈纳米颗粒(CeO NPs)、二氧化硅纳米颗粒(SiO2 NPs)和CeO-SiO2纳米复合材料(超级纳米复合材料)是研究领域中最有前途的新进展。CeO-SiO2纳米复合材料(超级纳米复合材料)是生物应用中最受欢迎的金属氧化物纳米复合材料之一,它具有优异的生物相容性,而且价格低廉,毒性低。CeO纳米颗粒(CeO NP)、二氧化硅纳米颗粒(SiO2 NP)和CeO-SiO2纳米复合材料(超级纳米复合材料)在生物医学领域,特别是在抗糖尿病、抗炎和抗菌领域都显示出了前景。为了对抗各种细菌,开发了超纳米复合物浓度(50µL/mL)。在这种情况下,二氧化硅纳米颗粒(SiO2 NP)、氧化铈纳米颗粒(CeO NP)和CeO-SiO2纳米复合材料(超级纳米复合材料)在抑制区具有更大的抗菌活性。还评估了SiO2 NP、CeO NP和CeO-SiO2纳米复合物(超级纳米复合物)的各种体外生物活性,包括它们的抗炎和抗糖尿病特性。与SiO2纳米颗粒和CeO纳米颗粒相比,超级纳米复合材料表现出更大的抗炎和抗糖尿病特性。在本研究中,使用碱性沉淀法生产了SiO2 NPs、CeO NPs和CeO-SiO2纳米复合材料(超级纳米复合材料)。利用XRD、SEM-EDX、FTIR、UV和TGA对SiO2 NP、CeO NP和CeO-SiO2纳米复合材料(超级纳米复合材料)进行了表征。该研究表明,就体外生物活性而言,CeO-SiO2纳米复合材料(超级纳米复合材料)优于SiO2 NPs和CeO-NPs。本研究强调了可持续生产CeO-SiO2纳米复合材料(超级纳米复合材料)用于生物医学应用的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Novel super nanocomposite (CeO-SiO2 nanocomposite) with enhanced biological application: Synthesis and characterization

Cerium Oxide nanoparticles (CeO NPs), Silica nanoparticles (SiO2 NPs), and CeO-SiO2 nanocomposite (Super Nanocomposite) are some of the most promising new developments in the field of investigation. One of the most popular metal oxide nanocomposites in biological applications is CeO-SiO2 nanocomposite (Super Nanocomposite), which has excellent biocompatibility and is also inexpensive and low-toxic. CeO nanoparticles (CeO NPs), Silica nanoparticles (SiO2 NPs), and CeO-SiO2 nanocomposite (Super Nanocomposite) have all demonstrated promise in the field of biomedicine, particularly in the anti-diabetic, anti-inflammatory, and antibacterial fields. In order to combat various bacterial species, Super Nanocomposite concentrations (50 µL/mL) were developed. In this case, silica nanoparticles (SiO2 NPs), cerium oxide nanoparticles (CeO NPs), and CeO-SiO2 nanocomposite (Super Nanocomposite) have greater antibacterial activity in the zone of inhibition. SiO2 NPs, CeO NPs, and CeO-SiO2 Nanocomposite (Super Nanocomposite) various in-vitro biological activities were also assessed, including their anti-inflammatory and anti-diabetic properties. In comparison to SiO2 NPs and CeO NPs, Super Nanocomposite exhibits greater anti-inflammatory and anti-diabetic characteristics. In this study, SiO2 NPs, CeO NPs, and CeO-SiO2 nanocomposite (Super Nanocomposite) were produced using a basic precipitation method. It was established that SiO2 NPs, CeO NPs, and CeO-SiO2 Nanocomposite (Super Nanocomposite) have been characterized utilizing XRD, SEM-EDX, FTIR, UV, and TGA. This study shown that CeO-SiO2 Nanocomposite (Super Nanocomposite) outperformed SiO2 NPs and CeO NPs in terms of in vitro bioactivities. This study emphasises the importance of producing CeO-SiO2 nanocomposite (Super Nanocomposite) materials sustainably for biomedical applications.

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