冷冻干燥法稳定化妆品油水乳液中不稳定活性成分。

IF 1 4区生物学 Q3 BIOLOGY

Cryo letters Pub Date : 2023-03-01

Z X Yi, M Yang, B L Liu

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引用次数: 0

摘要

背景：由于油/水乳液的不稳定性，某些不稳定的活性成分通常不用于化妆品。目的：考察冷冻干燥对油/水化妆品乳液的稳定性。材料和方法：在量热法和冷冻干燥显微镜研究的基础上，建立了初步的冷冻干燥工艺。结果：加速稳定性实验表明，冷冻干燥乳液在48℃下28天后保留了90.1%的维生素C，而油水乳液仅保留了28.3%的维生素C。冷冻干燥乳液比油水乳液具有明显更少的油氧化。结论：冷冻干燥提高了化妆品乳液中维生素C及油性活性成分的稳定性。DOI:10.54680/fr23210110312。

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Stabilization of labile active ingredients in an oil-water emulsion cosmetics by freeze-drying.

Background: Due to the instability in oil/water emulsion, certain labile active ingredients were often not used in cosmetics.

Objective: The present study has tested the effect of freeze-drying to stabilize an oil/water cosmetic emulsion.

Materials and methods: A preliminary freeze-drying process was established at the basis of calorimetric and freeze-drying microscope studies. The stability of labile molecules in the cosmetic emulsion was evaluated at 48 degree C after freeze-drying.

Results: The accelerated stability experiment showed that the freeze-dried emulsion retained 90.1% vitamin C after 28 days at 48 degree C, whereas the oil-water emulsion retained only 28.3% vitamin C. The freeze-dried emulsion had significantly less oil oxidation than did the oil-water emulsion.

Conclusion: Freeze-drying improved the stability of vitamin C and oily active ingredients in cosmetic emulsions. DOI: 10.54680/fr23210110312.

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来源期刊

Cryo letters 生物-生理学

CiteScore

1.80

自引率

10.00%

发文量

审稿时长

1 months

期刊介绍： A bimonthly international journal for low temperature sciences, including cryobiology, cryopreservation or vitrification of cells and tissues, chemical and physical aspects of freezing and drying, and studies involving ecology of cold environments, and cold adaptation The journal publishes original research reports, authoritative reviews, technical developments and commissioned book reviews of studies of the effects produced by low temperatures on a wide variety of scientific and technical processes, or those involving low temperature techniques in the investigation of physical, chemical, biological and ecological problems.