{"title":"真皮填充物的未来","authors":"Nicholas Strat, Alan Snyder, Todd Schlesinger","doi":"10.1002/der2.188","DOIUrl":null,"url":null,"abstract":"<p>The advancement of dermal fillers has progressed from animal collagen extraction to a spectrum of recombinant DNA, nanotechnology, and biostimulation. Consumers now have a variety of fillers to choose from, including organic fillers composed of hyaluronic acid and calcium hydroxyapatite, as well as synthetic fillers made from poly-<span>l</span>-lactic acid and polymethylmethacrylate. This piece serves to add to the open dialogue discussing the prognosis, prospects, and potential pitfalls of dermal fillers. Expansion of product indications and technical alterations are currently changing the dermal fillers' landscape. The potential for new approaches to side effect mitigation or adjunct pigment modification is still exploratory. Furthermore, with social implications increasingly coming into frame, healthcare providers and companies seem geared toward developing effective, safe, and equitable products while maintaining a process of rigorous review and quality control processes. As such, future developments of this medical tool appear promising; fillers seem poised to imbue a role as dynamic as the tissues they were conceived to restore.</p>","PeriodicalId":100366,"journal":{"name":"Dermatological Reviews","volume":"4 3","pages":"139-142"},"PeriodicalIF":0.0000,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Future of dermal fillers\",\"authors\":\"Nicholas Strat, Alan Snyder, Todd Schlesinger\",\"doi\":\"10.1002/der2.188\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>The advancement of dermal fillers has progressed from animal collagen extraction to a spectrum of recombinant DNA, nanotechnology, and biostimulation. Consumers now have a variety of fillers to choose from, including organic fillers composed of hyaluronic acid and calcium hydroxyapatite, as well as synthetic fillers made from poly-<span>l</span>-lactic acid and polymethylmethacrylate. This piece serves to add to the open dialogue discussing the prognosis, prospects, and potential pitfalls of dermal fillers. Expansion of product indications and technical alterations are currently changing the dermal fillers' landscape. The potential for new approaches to side effect mitigation or adjunct pigment modification is still exploratory. Furthermore, with social implications increasingly coming into frame, healthcare providers and companies seem geared toward developing effective, safe, and equitable products while maintaining a process of rigorous review and quality control processes. As such, future developments of this medical tool appear promising; fillers seem poised to imbue a role as dynamic as the tissues they were conceived to restore.</p>\",\"PeriodicalId\":100366,\"journal\":{\"name\":\"Dermatological Reviews\",\"volume\":\"4 3\",\"pages\":\"139-142\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-04-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Dermatological Reviews\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/der2.188\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dermatological Reviews","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/der2.188","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The advancement of dermal fillers has progressed from animal collagen extraction to a spectrum of recombinant DNA, nanotechnology, and biostimulation. Consumers now have a variety of fillers to choose from, including organic fillers composed of hyaluronic acid and calcium hydroxyapatite, as well as synthetic fillers made from poly-l-lactic acid and polymethylmethacrylate. This piece serves to add to the open dialogue discussing the prognosis, prospects, and potential pitfalls of dermal fillers. Expansion of product indications and technical alterations are currently changing the dermal fillers' landscape. The potential for new approaches to side effect mitigation or adjunct pigment modification is still exploratory. Furthermore, with social implications increasingly coming into frame, healthcare providers and companies seem geared toward developing effective, safe, and equitable products while maintaining a process of rigorous review and quality control processes. As such, future developments of this medical tool appear promising; fillers seem poised to imbue a role as dynamic as the tissues they were conceived to restore.