Dolores Di Vizio, Melanie Schoppet, Ashani Weeraratna, Kenneth W. Witwer
{"title":"斑点和以前的斑点：从表面突起到癌症信号传导中的细胞外小泡，失活细胞耐药性及其他","authors":"Dolores Di Vizio, Melanie Schoppet, Ashani Weeraratna, Kenneth W. Witwer","doi":"10.1002/jex2.112","DOIUrl":null,"url":null,"abstract":"<p>Associations between plasma membrane blebbing and metastatic progression have been widely reported. There are also reports of increased extracellular vesicle (EV) release from cancer cells. Yet the ties between these closely related phenomena are incompletely understood. In this commentary, we remark on a recent finding on cellular membrane blebs in melanoma signalling. We discuss possible implications for cancer biology and draw parallels to knowns and unknowns in the relationships of EVs and cancer progression.</p>","PeriodicalId":73747,"journal":{"name":"Journal of extracellular biology","volume":"2 10","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jex2.112","citationCount":"0","resultStr":"{\"title\":\"Blebs and former blebs: From surface protrusions to extracellular vesicles in cancer signalling, anoikis resistance and beyond\",\"authors\":\"Dolores Di Vizio, Melanie Schoppet, Ashani Weeraratna, Kenneth W. Witwer\",\"doi\":\"10.1002/jex2.112\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Associations between plasma membrane blebbing and metastatic progression have been widely reported. There are also reports of increased extracellular vesicle (EV) release from cancer cells. Yet the ties between these closely related phenomena are incompletely understood. In this commentary, we remark on a recent finding on cellular membrane blebs in melanoma signalling. We discuss possible implications for cancer biology and draw parallels to knowns and unknowns in the relationships of EVs and cancer progression.</p>\",\"PeriodicalId\":73747,\"journal\":{\"name\":\"Journal of extracellular biology\",\"volume\":\"2 10\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-10-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jex2.112\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of extracellular biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/jex2.112\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of extracellular biology","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jex2.112","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Blebs and former blebs: From surface protrusions to extracellular vesicles in cancer signalling, anoikis resistance and beyond
Associations between plasma membrane blebbing and metastatic progression have been widely reported. There are also reports of increased extracellular vesicle (EV) release from cancer cells. Yet the ties between these closely related phenomena are incompletely understood. In this commentary, we remark on a recent finding on cellular membrane blebs in melanoma signalling. We discuss possible implications for cancer biology and draw parallels to knowns and unknowns in the relationships of EVs and cancer progression.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
