真菌肌球蛋白-1同源物作为膜-细胞骨架界面的关键分子马达

IF 5.7 2区 生物学 Q1 MYCOLOGY
Qin-Rong Tan , Xiang-dong Li
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引用次数: 0

摘要

I类肌球蛋白(肌球蛋白1)是一种小型的单头肌球蛋白,分布于低等真核生物(如真菌)和高等真核动物(如脊椎动物)。肌球蛋白1能够通过运动结构域与肌动蛋白相互作用,并通过尾部结构域与膜结合,在膜-细胞骨架界面发挥许多基本功能。在真菌中,肌球蛋白1对许多细胞过程至关重要,包括内吞作用、菌丝生长、内质网(ER)重塑和致病性。本文综述了近年来真菌肌球蛋白1的研究进展。我们首先介绍了每个真菌肌球蛋白结构域的基本结构和功能,然后将最近解决的真菌肌球蛋白1与脊椎动物肌球蛋白1的三维结构进行了比较,最后重点讨论了真菌肌球蛋白-1如何参与胞吞作用和ER重塑。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fungal myosin-1 homologs as key molecular motors at the membrane–cytoskeleton interface
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来源期刊
CiteScore
10.60
自引率
0.00%
发文量
36
期刊介绍: Fungal Biology Reviews is an international reviews journal, owned by the British Mycological Society. Its objective is to provide a forum for high quality review articles within fungal biology. It covers all fields of fungal biology, whether fundamental or applied, including fungal diversity, ecology, evolution, physiology and ecophysiology, biochemistry, genetics and molecular biology, cell biology, interactions (symbiosis, pathogenesis etc), environmental aspects, biotechnology and taxonomy. It considers aspects of all organisms historically or recently recognized as fungi, including lichen-fungi, microsporidia, oomycetes, slime moulds, stramenopiles, and yeasts.
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