骨软骨技术:我们现在在哪里?

Giovanna Medina, Simon Görtz
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引用次数: 0

摘要

透明关节软骨是一种独特的、高度特化的组织,具有独特的结构,在成人受伤时缺乏有效愈合的内在手段。对于临床和科学界来说,症状性骨关节缺损仍然是一个巨大的挑战。在为此目的提出的各种手术治疗方案中,只有骨软骨移植技术能够可靠地在获得性关节软骨病变中恢复适当的透明组织,特别是当这些病变涉及软骨下骨时。对于外科医生来说,自体和异体移植都是可用的,他们必须在治疗算法中考虑每种方法的独特品质和特征。自体移植物和同种异体移植物都遵循相同的方法,依靠成熟骨软骨结构的骨愈合来移植附着的可存活关节软骨。所需的手术技术是直接和可复制的,但需要精确地恢复关节表面的一致性,实现可靠的骨长入,并最终取得临床成功。为了进一步验证临床经验,提高种植体的质量和安全性,科学研究正在进行中,这对骨软骨移植在关节保存方面的未来有很大的希望。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Osteochondral techniques: where are we now?

Hyaline articular cartilage is a unique, highly specialized tissue with a distinct architecture that lacks intrinsic means to heal effectively when injured in the adult. Symptomatic osteoarticular defects continue to be a formidable challenge for the clinical and scientific communities alike. Of the various surgical treatment options that have been proposed to this end, only osteochondral grafting techniques reliably restore appropriate hyaline tissue in acquired articular cartilage lesions, especially when these involve the subchondral bone. Both autologous and allogeneic graft sources are available to the surgeon, who must consider the unique qualities and characteristics of either approach in the treatment algorithm. Autografts and allografts alike adhere to a common methodology, relying on osseous healing of mature osteochondral constructs to transplant the adherent viable articular cartilage. The required surgical technique is straightforward and reproducible but requires precision to restore articular surface congruity, achieve reliable bony ingrowth, and, ultimately, clinical success. Scientific investigation to further validate empirical clinical practice and to improve implant quality and safety is ongoing and holds great promise for the future of osteochondral grafting in joint preservation.

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