西班牙高胆固醇血症的控制:具有不同自治现实的同一情况

IF 1.9 Q3 PERIPHERAL VASCULAR DISEASE
Juan Pedro-Botet , Núria Plana , José María Mostaza , Juan José Gómez-Doblas , María Rosa Fernández Olmo , Carlos Escobar Cervantes , José Luis Díaz-Díaz , Raquel Campuzano Ruiz , Pedro Valdivielso , Juan Cosín-Sales
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引用次数: 0

摘要

引言和目的由于卫生能力的转移,自治社区的心血管预防策略可能会发生变化。本研究的目的是确定自治社区对高/极高心血管风险(CVR)患者的血脂异常控制程度和降脂药物治疗。方法基于一致性方法的观察、横断面、描述性研究。通过面对面会议和对435名参与医生进行问卷调查,收集了西班牙17个自治社区145个卫生区的临床实践信息。此外,从每个参与者最近访问过的10名连续的血脂异常患者中汇编了不可识别的汇总数据。结果4010例患者中,649例(16%)CVR偏高,2458例(61%)CVR极高。3107名高/极高CVR患者的分布在各地区之间是平衡的,但在实现目标LDL-C<;70和<;分别为55mg/dL。在44%、21%和4%的高CVR患者中使用了单药治疗或与依折麦布和/或PCSK9抑制剂联合使用的高强度他汀类药物,而在CVR极高的患者中,这一比例分别上升到38%、45%和6%。在国家层面上,这些降脂疗法的使用在不同地区之间存在显著差异(P=0.0079)。结论尽管高/极高CVR患者在自治社区之间的分布相似,但在实现低密度脂蛋白胆固醇治疗目标和使用降脂疗法的程度上,地区间存在差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Control de la hipercolesterolemia en España: una misma situación con diferentes realidades autonómicas

Introduction and objective

The cardiovascular prevention strategy by autonomous communities can be variable since the competences in health are transferred. The objective of the study was to determine the degree of dyslipidaemia control and the lipid-lowering pharmacological therapy used in patients at high/very high cardiovascular risk (CVR) by autonomous communities.

Methods

Observational, cross-sectional, descriptive study based on a consensus methodology. Information on the clinical practice of 145 health areas belonging to 17 Spanish autonomous communities was collected through face-to-face meetings and questionnaires administered to the 435 participating physicians. Furthermore, aggregate non-identifiable data were compiled from 10 consecutive dyslipidaemic patients that each participant had recently visited.

Results

Of the 4010 patients collected, 649 (16%) had high and 2458 (61%) very high CVR. The distribution of the 3107 high/very high CVR patients was balanced across regions, but there were inter-regional differences (P < .0001) in the achievement of target LDL-C < 70 and < 55 mg/dL, respectively. High-intensity statins in monotherapy or in combination with ezetimibe and/or PCSK9 inhibitors were used in 44, 21 and 4% of high CVR patients, while in those at very high CVR it rose to 38, 45 and 6%, respectively. The use of these lipid-lowering therapies at national level was significantly different between regions (P = .0079).

Conclusions

Even though the distribution of patients at high/very high CVR was similar between autonomous communities, inter-territorial differences were identified in the degree of achievement of LDL cholesterol therapeutic goal and use of lipid-lowering therapy.

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来源期刊
Clinica e Investigacion en Arteriosclerosis
Clinica e Investigacion en Arteriosclerosis PERIPHERAL VASCULAR DISEASE-
CiteScore
3.20
自引率
6.20%
发文量
44
审稿时长
40 days
期刊介绍: La publicación idónea para acceder tanto a los últimos originales de investigación como a formación médica continuada sobre la arteriosclerosis y su etiología, epidemiología, fisiopatología, diagnóstico y tratamiento. Además, es la publicación oficial de la Sociedad Española de Arteriosclerosis.
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