拉丁美洲的系统性红斑狼疮:结果和治疗挑战

Manuel F. Ugarte-Gil , Graciela S. Alarcón
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引用次数: 0

摘要

系统性红斑狼疮(SLE)对非白人人群的影响更为严重,拉丁美洲也是如此;这是遗传和非遗传因素共同作用的结果。在非遗传因素中,收入有限和教育水平低对疾病的进程和结果产生负面影响;此外,缺乏医疗服务使患者失去了由专家管理的机会,使最新药物的供应几乎不可能。综合来看,这些因素降低了患者获得良好结果的概率,如病情缓解、损伤减少、生存率提高和健康相关生活质量提高等。已经提出了一些减少这些差异的战略,包括同伴教育、为患者和初级保健医生开展教育活动、改善医疗保健网络和进行成本效益分析。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Systemic lupus erythematosus in Latin America: Outcomes and therapeutic challenges

Systemic lupus erythematosus (SLE) affects more severely non-White populations, which is also the case in Latin America; this is the result of a combination of genetic and non-genetic factors. Among the non-genetic factors, a limited income and a low educational level impact negatively on the course and outcome of the disease; in addition, lack of access to healthcare services deprives patients from the opportunity of being managed by specialists, making the availability of the newest drugs practically impossible. Taking together, these factors reduce the probability of patients achieving good outcomes, like remission, less damage accrual, a better survival and a better health-related quality of life, among others. Several strategies have been proposed to reduce these disparities, including peer education, educational activities for patients and primary care physicians, improving healthcare networks and generating cost-effectiveness analyses.

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