转录组分析证实水生动物携带人类呼吸道病毒的风险较小

Yuan Chen , Tingsong Yue , Guoliang Lin , Xi Luo , Huimin Yang , Robert W. Murphy , Siyuan Gao , Jing Luo
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引用次数: 0

摘要

水生动物是人类的重要食物来源,但人们对其传播人畜共患病毒的潜力知之甚少。最近从冷链水生食品和环境样本中发现的多例严重急性呼吸系统综合征冠状病毒2型病例引起了全世界的关注,尽管这些病例与家禽和牲畜相比相形见绌。为了研究水生动物食物的潜在威胁,我们将它们的转录组映射到人类呼吸道和肠道相关病毒的基因组中。分析仅在三文鱼(Salmo salar)皮肤转录组中发现流感病毒序列。BLAST和系统发育分析确定该序列为甲型流感,这可能是由于工人的污染。因此,如果准备得当,水生动物可以为人类提供巨大的营养益处,同时将健康风险降至最低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Transcriptome analysis confirms aquatic animals has less risk by carrying on human respiratory viruses

Aquatic animals are an important source of food for humans, yet little is known about their potential to transfer zoonotic viruses. Multiple recent cases of SARS-CoV-2 from cold-chain aquatic food and environmental samples has evoked worldwide concerns, and even though these cases pale in comparison to poultry and livestock. To investigate the potential threat of food from aquatic animals, we map their transcriptomes to the genomes of human respiratory- and intestine-related viruses. Analyses only find an influenza virus sequence in a salmon (Salmo salar) skin transcriptome. BLAST and phylogenetic analyses identify this sequence as influenza A, and this likely owes to contamination from a worker. Thus, when prepared properly, aquatic animals can provide great nutritional benefits to humans while posing minimal health risks.

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