强化正念和瑜伽对患有人格障碍的囚犯的可行性和初步结果:一项随机对照初步研究

Ivana Buric , Miguel Farias , Stoyan Kurtev , Valerie van Mulukom , Christopher Mee , Lloyd Gould , Sabeela Rehman , Barbara Parker , Inti A. Brazil
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引用次数: 1

摘要

这项研究首次在包含所有十种类型人格障碍的样本中采用随机对照研究设计来测试身心干预的可行性,并首次使用心理、基因组、神经和行为测量相结合的方法对反应进行初步评估。30名患有人格障碍的囚犯被招募到一所戒备森严的监狱的临床单元,并被分配到正念干预组(n=10)、瑜伽干预组(n=10)或等待名单对照组(n=0)。正念和瑜伽干预同时进行,连续五天每天持续三个小时。在基线和干预后,我们通过静脉血测量炎症相关基因的表达;具有认知任务的注意力;脑电事件相关电位;以及压力、情绪调节和正念的问卷调查。在这里,我们表明,招聘率和辍学率令人满意,尽管数据收集时间长且复杂,但数据收集是成功的。唯一的例外是血液样本,60%的参与者拒绝献血,但这是意料之中的,因为47%的招募参与者被诊断为偏执性人格障碍。当参与者没有完全遵守随机化程序时,出现了意想不到的困难,在干预的最后一天发生了骚乱。这项研究无法检测主要或次要结果指标的变化,但尽管80%的炎症相关基因显示出中等和较大的影响大小,这表明这是未来研究中的一项重要结果指标。在进行更大规模的研究以准确确定正念和瑜伽作为人格障碍囚犯的额外治疗方法的效果之前,有必要对研究设计进行微小的调整。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Feasibility and preliminary outcomes of intensive mindfulness and yoga on prisoners with personality disorders: A randomised controlled preliminary study

This study was the first to test the feasibility of mind-body interventions with a randomised control research design in a sample that contains all ten types of personality disorders, and the first to provide a preliminary evaluation of responses using a combination of psychological, genomic, neural, and behavioural measures. Thirty prisoners with personality disorders were recruited within a clinical unit of a high security prison and assigned to a mindfulness intervention (n=10), a yoga intervention (n=10), or a wait-list control group (n=10). Both mindfulness and yoga interventions were held simultaneously and lasted three hours per day on five consecutive days. At baseline and after the intervention, we measured inflammation-related gene expression through venous blood; attention with a cognitive task; event-related potentials (ERPs) with EEG; and stress, emotion regulation and mindfulness with questionnaires. Here we show that recruitment and dropout rates were satisfactory, and data collection was successful despite its length and complexity. The only exception were blood samples where 60% of participants refused to give blood, but this was expected because 47% of recruited participants had a diagnosis of paranoid personality disorder. Unexpected difficulties occurred when participants did not fully adhere to randomisation procedures, and a riot took place during the final day of the interventions. This study was underpowered to detect changes on primary or secondary outcome measures, but despite that 80% of examined inflammation-related genes showed medium and large effect sizes suggesting this as an important outcome measure in future studies. Minor adjustments to the study design are necessary before a larger scale study can be conducted to precisely determine the effects of mindfulness and yoga as an additional treatment for prisoners with personality disorders.

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