基底细胞癌的治疗:临床经验

IF 0.7 Q4 OTORHINOLARYNGOLOGY
Irfan Kara, Alperen Vural, M. Ünlü, Furkan Şan, Gülten Benan Göçer, Muhammed Gazi Yıldız
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摘要

目的:基底细胞癌主要起源于头颈部。BCC治疗的主要目标是在遵守肿瘤手术原则的同时达到美观和功能的效果。我们根据文献报道了我们关于头颈部基底细胞癌的临床、组织病理学特征和手术治疗结果的经验。方法:回顾性分析两所大学医院手术治疗头颈部基底细胞癌的病例资料。评估了社会形态变量、肿瘤的位置和大小、病理亚型、复发率、并发症和重建技术。结果:我们分析了105例患者的119个肿瘤病变,其中55例(52.4%)为男性,50例(47.6%)为女性。平均年龄67.3±12岁。鼻区是最常见的位置区域(n=42,35.3%)。平均肿瘤大小为12.6 mm,肿瘤大小范围为2–85 mm。最常用的重建技术是皮瓣手术,然后是初次闭合和皮肤移植。结论:重要的是在术中以至少4mm的清晰手术边缘切除肿瘤,并用冷冻切片评估五种手术边缘。手术通常在局部麻醉下进行,患者耐受性良好。重建中使用的最常见的皮瓣不仅易于学习,而且在大多数情况下也足够了。皮肤移植物是很好的选择,在缺陷位于腔甲和外耳道。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Management of Basal Cell Carcinomas: Clinical Experience
Objective: Basal cell carcinomas (BCC) mostly originate from the head and neck region. Main goal in BCC treatment is to achieve both aesthetic and functional results while observing the principles of tumor surgery. We report our experience regarding the clinical, histopathological features and surgical treatment results of head and neck basal cell carcinomas in the light of the literature. Methods: Files of patients with head and neck BCCs treated surgically in two university hospitals were retrospectively analyzed. Sociodemographic variables, location and size of tumor, pathological subtype, recurrence ratio, complications and technique of reconstruction were evaluated. Results: We analyzed 119 tumoral lesions in 105 patients of whom 55 (52.4%) were male and 50 (47.6%) were female. Their mean age was 67.3±12 years. The nasal region was the most common location area (n=42, 35.3%). Mean tumor size was 12.6 mm and tumor size range was 2–85 mm. The most commonly used reconstruction techniques were flap surgery, followed by primary closure, and skin grafts. Conclusion: It is important to remove the tumor with a clear surgical margin at least 4 mm and evaluate the five surgical margins with frozen sections intraoperatively. Operations are often performed under local anesthesia and are well tolerated by patients. The most common flaps used in the reconstruction are not only easy to learn but also sufficient in most cases. Skin grafts are good choices in defects located in the cavum concha and the external meatus.
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