一例罕见的超声标记对进化性皮质畸形的产前诊断

IF 0.1 Q4 OBSTETRICS & GYNECOLOGY

Journal of Fetal Medicine Pub Date : 2023-05-16 DOI:10.1055/s-0043-57036

Aditi Shah, Navya Bharathi, Tejaswi Reddy

{"title":"一例罕见的超声标记对进化性皮质畸形的产前诊断","authors":"Aditi Shah, Navya Bharathi, Tejaswi Reddy","doi":"10.1055/s-0043-57036","DOIUrl":null,"url":null,"abstract":"Abstract Malformations of cortical development are rarely diagnosed in utero. Cortical malformations are aberrations in the process of corticogenesis. We report two rare and unique cases of evolving cortical malformation with unusual ultrasonogram markers: (1) narrow cavum septum pellucidum and (2) ill-defined and irregular lateral ventricular borders on the midtrimester anomaly scan. This was further confirmed by fetal brain evaluation on magnetic resonance imaging with additional information on irregular ventricular borders, scattered hyperintensities in the cerebral parenchyma and periventricular area, loss of cerebral layering pattern at 24 weeks gestation in one case, and hemimegalencephaly in another case with a probable diagnosis of evolving cortical malformation. Literature review reveals the above as an unusual presentation on the anomaly scan.","PeriodicalId":42412,"journal":{"name":"Journal of Fetal Medicine","volume":null,"pages":null},"PeriodicalIF":0.1000,"publicationDate":"2023-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Case Report on Prenatal Diagnosis of Evolving Cortical Malformations: A Rare Ultrasound Marker\",\"authors\":\"Aditi Shah, Navya Bharathi, Tejaswi Reddy\",\"doi\":\"10.1055/s-0043-57036\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract Malformations of cortical development are rarely diagnosed in utero. Cortical malformations are aberrations in the process of corticogenesis. We report two rare and unique cases of evolving cortical malformation with unusual ultrasonogram markers: (1) narrow cavum septum pellucidum and (2) ill-defined and irregular lateral ventricular borders on the midtrimester anomaly scan. This was further confirmed by fetal brain evaluation on magnetic resonance imaging with additional information on irregular ventricular borders, scattered hyperintensities in the cerebral parenchyma and periventricular area, loss of cerebral layering pattern at 24 weeks gestation in one case, and hemimegalencephaly in another case with a probable diagnosis of evolving cortical malformation. Literature review reveals the above as an unusual presentation on the anomaly scan.\",\"PeriodicalId\":42412,\"journal\":{\"name\":\"Journal of Fetal Medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.1000,\"publicationDate\":\"2023-05-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Fetal Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1055/s-0043-57036\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Fetal Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/s-0043-57036","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

摘要皮质发育畸形很少在子宫内被诊断出来。皮质畸形是皮质发生过程中的异常现象。我们报告了两例罕见且独特的具有异常超声标记的进化性皮质畸形病例：（1）狭窄的透明隔腔和（2）中期异常扫描中定义不清且不规则的侧脑室边界。胎儿大脑对磁共振成像的评估进一步证实了这一点，磁共振成像提供了关于心室边界不规则、脑实质和心室周围区域分散性高信号、一例在妊娠24周时大脑分层模式丧失以及另一例可能诊断为发展中的皮质畸形的脑偏大的额外信息。文献综述显示，上述异常扫描表现异常。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

A Case Report on Prenatal Diagnosis of Evolving Cortical Malformations: A Rare Ultrasound Marker

Abstract Malformations of cortical development are rarely diagnosed in utero. Cortical malformations are aberrations in the process of corticogenesis. We report two rare and unique cases of evolving cortical malformation with unusual ultrasonogram markers: (1) narrow cavum septum pellucidum and (2) ill-defined and irregular lateral ventricular borders on the midtrimester anomaly scan. This was further confirmed by fetal brain evaluation on magnetic resonance imaging with additional information on irregular ventricular borders, scattered hyperintensities in the cerebral parenchyma and periventricular area, loss of cerebral layering pattern at 24 weeks gestation in one case, and hemimegalencephaly in another case with a probable diagnosis of evolving cortical malformation. Literature review reveals the above as an unusual presentation on the anomaly scan.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Journal of Fetal Medicine OBSTETRICS & GYNECOLOGY-

自引率

50.00%

发文量

期刊介绍： Journal of Fetal Medicine is the official journal of the Society of Fetal Medicine affiliated with International Society of Ultrasound in Obstetrics & Gynecology. This is a peer-reviewed international journal featuring articles with special interest to fetal medicine specialists, geneticists and ulstrasonologists. The aim of the journal is to communicate the results of original research in the field of fetal medicine. It includes a variety of articles suitable for clinicians and scientific specialists concerned with diagnosis and therapy of fetal disorders. All articles on health promotion of the fetus are acceptable for publication. The major focus is on highlighting the work that has been carried out in India and other developing countries. It also includes articles written by experts from the West. Types of articles published: - Original research articles related to fetal care and basic research - Review articles - Consensus guidelines for diagnosis and treatment - Case reports - Images in Fetal Medicine - Brief communications