伊朗大不里士接种新冠肺炎疫苗和未接种疫苗孕妇的妊娠结局和新生儿并发症的比较

IF 1.1 Q4 IMMUNOLOGY
S. Taghavi, M. Dehdilani, M. Dehdilani
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引用次数: 0

摘要

简介:关于2019冠状病毒病(新冠肺炎)孕妇疫苗接种安全性的信息不足。目的:本研究比较了接种新冠肺炎疫苗和未接种疫苗的孕妇的妊娠和胎儿结局。患者和方法:这项横断面研究是在大不里士医学科学大学(伊朗大不里士)对117名孕妇(55名接种疫苗的妇女为病例组,62名未接种疫苗的女性为对照组)进行的,使用2022年的人口普查抽样。产妇结局(死亡、入住重症监护室、早产、妊娠期高血压、先兆子痫、羊水过少和羊水过多)和新生儿结局(新生儿死亡、先天性残疾、新生儿体重减轻、入住ICU、新生儿感染、新生儿发烧、新生儿需要机械通气以及1分钟和5分钟Apgar评分)分别为记录。然后使用独立t检验、方差分析和卡方检验对两组进行比较。结果:病例组无妊娠结局的妇女人数略低于对照组(P=0.099)。未接种疫苗的妇女的妊娠高血压(P=0.312)和早产率低于接种疫苗的女性,但这一差异并不显著(P=0.089)。新生儿重症监护室住院(P=0.361)、新生儿发烧(P=0.259),新生儿感染(P=0.079)在接种疫苗的母亲所生婴儿中比未接种疫苗的妇女所生婴儿更常见,尽管差异不显著。结论:接种新冠肺炎疫苗似乎与增加孕产妇和新生儿并发症的概率无关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison of pregnancy outcomes and neonatal complications between COVID–19-vaccinated and unvaccinated pregnant women in Tabriz, Iran
Introduction: Insufficient information exists regarding the coronavirus disease 2019 (COVID-19) vaccination safety in pregnant women. Objectives: The present study compared the pregnancy and fetal outcomes among COVID-19-vaccinated and unvaccinated pregnant women. Patients and Methods: This cross-sectional study was conducted at Tabriz University of Medical Sciences (Tabriz, Iran) on 117 pregnant women (55 vaccinated women as the case group and 62 unvaccinated women as the control group) using census sampling in 2022. The maternal outcomes (death, admission to intensive care unit [ICU], premature birth, gestational hypertension, preeclampsia, oligohydramnios, and polyhydramnios) and neonatal outcomes (neonatal death, congenital disabilities, neonatal weight loss, admission to ICU, neonatal infection, neonatal fever, need for mechanical ventilation of the newborn, and one- and five-minute Apgar scores) were recorded. Then the two groups were compared using independent t-test, along with ANOVA and chi-square tests. Results: The number of women without pregnancy outcomes was marginally lower in the case group than in the control group (P=0.099). Gestational hypertension (P=0.312) and preterm birth were lower among unvaccinated women than among vaccinated women but this difference was not significant (P=0.089). Hospitalization in the neonatal intensive care unit (P=0.361), neonatal fever (P=0.259), and neonatal infection (P=0.079) were more common in infants born to vaccinated mothers than in infants born to unvaccinated women, although the difference not significant. Conclusion: Vaccination against COVID-19 appears to not be associated with an increased probability of maternal and neonatal complications.
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来源期刊
CiteScore
1.70
自引率
0.00%
发文量
65
审稿时长
3 weeks
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