Nitika Sanger, Balpreet Panesar, Michael Dennis, Tea Rosic, Myanca Rodrigues, Elizabeth Lovell, Shuling Yang, Mehreen Butt, Lehana Thabane, Zainab Samaan
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However, patients receiving medication for opioid use disorder treatment (MOUD) may prioritise the use of different ways to assess treatment success.</p><p><strong>Objective: </strong>The aim of this review is to synthesize literature examining the self-reported goals patients would like to achieve in MOUD for opioid use disorder.</p><p><strong>Methods: </strong>We searched MEDLINE, EMBASE, PsycINFO, Cumulative Index to Nursing and Allied Health Literature, Web of Science, Cochrane Library, Cochrane Clinical Trials Registry, the National Institutes for Health Clinical Trials Registry, and the WHO International Clinical Trials Registry Platform from inception until April 30th, 2021. No restrictions were placed on language, age, or type of MOUD. A qualitative synthesis is presented given that a meta-analysis was not possible.</p><p><strong>Results: </strong>The search yielded a total of 21,082 records from which 8 met criteria for inclusion in the qualitative synthesis. 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引用次数: 0
摘要
引言在治疗阿片类药物使用障碍方面，现在比以往任何时候都更需要以患者为中心的护理。试验、政策制定者和服务提供者最常使用治疗保留和阿片类药物尿液筛查作为治疗效果的衡量标准。然而，接受阿片类药物使用障碍治疗的患者可能会优先使用不同的方法来评估治疗成功率。目的本综述的目的是综合文献，研究患者在阿片类药物使用障碍的MOUD中希望实现的自我报告目标。方法从成立到2021年4月30日，我们搜索了MEDLINE、EMBASE、PsycINFO、护理和相关健康文献累积指数、Web of Science、Cochrane图书馆、Cochran临床试验注册中心、美国国立卫生研究院临床试验注册处和世界卫生组织国际临床试验注册平台。对语言、年龄或MOUD类型没有任何限制。在不可能进行荟萃分析的情况下，进行了定性综合。结果检索共产生21082份记录，其中8份符合纳入定性综合的标准。我们从8项研究中确定了总共43名患者报告的治疗目标。根据报告的43个目标创建了12个领域。这些领域涵盖了患者目标的一系列重要领域，涉及正常生活、身体健康、心理健康、治疗和药物使用特定领域。结论这篇综述强调了他们在阿片类药物使用障碍治疗期间希望实现的几个患者目标，这些目标通常不被认为是治疗效果的标志。临床试验人员、研究人员、政策制定者、服务提供商、患者和参与制定和定制阿片类药物使用障碍治疗计划的社区应考虑到与健康、正常生活和患者总体药物使用相关的目标。系统审查注册PROSPERO CRD42018095553。
The Inclusion of Patients' Reported Outcomes to Inform Treatment Effectiveness Measures in Opioid Use Disorder. A Systematic Review.
Introduction: Patient centred care is needed now more than ever in the treatment of opioid use disorder. Trials, policy makers, and service providers have most often used treatment retention and opioid urine screens as measures of treatment effectiveness. However, patients receiving medication for opioid use disorder treatment (MOUD) may prioritise the use of different ways to assess treatment success.
Objective: The aim of this review is to synthesize literature examining the self-reported goals patients would like to achieve in MOUD for opioid use disorder.
Methods: We searched MEDLINE, EMBASE, PsycINFO, Cumulative Index to Nursing and Allied Health Literature, Web of Science, Cochrane Library, Cochrane Clinical Trials Registry, the National Institutes for Health Clinical Trials Registry, and the WHO International Clinical Trials Registry Platform from inception until April 30th, 2021. No restrictions were placed on language, age, or type of MOUD. A qualitative synthesis is presented given that a meta-analysis was not possible.
Results: The search yielded a total of 21,082 records from which 8 met criteria for inclusion in the qualitative synthesis. We identified a total of 43 patient-reported treatment goals from the 8 studies. Twelve domains were created from the 43 goals reported. These domains cover a range of important areas for patients' goals related to living a normal life, physical health, mental health, treatment, and substance use specific areas.
Conclusion: This review highlights several patient goals that they would like to achieve during treatment for opioid use disorder that are not commonly considered as markers of treatment effectiveness. Goals related to health, living a normal life, and overall substance use concerns by patients should be taken into consideration by clinical trialists, researchers, policy makers, service providers, patients, and communities engaged in developing and tailoring treatment plans for opioid use disorder.
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